Results 211 to 220 of about 400,342 (335)

High Grade Hepatotoxicity From Dual Checkpoint Inhibitors Is More Common in Hepatocellular Carcinoma Than Other Cancers. [PDF]

Liver Int
Ennin E, Mallepally N, Ali M, Shojaie L, Dewberry S, Trieu M, Torres ETR, Zhou K, Kahn J, Dodge JL, Dara L.   +10 more
europepmc   +1 more source

Clinical evaluation of three-dimensional (3D) power Doppler ultrasonography for depiction of hepatocellular carcinoma (HCC) compared with angiography

, 2000
Shinpei Sato, Shuichiro Shiina, Takuma Teratani, Shuntaro Obi, Keisuke Hamamura, Yukihiro Koike, Tomonori Fujishima, Yujin Hoshida, Ryosuke Tateishi, Yasuo Imai, Yasushi Shiratori, Masao Omata   +11 more
openalex   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Viral fusogenic membrane glycoproteins are a new class of therapeutic genes for the treatment of hepatocellular carcinoma (HCC)

, 2000
Hajime Higuchi, Steven F. Bronk, Richard G. Vile, Gregory J. Gores   +3 more
openalex   +1 more source

Efficacy of Sequential Hepatic Vein Embolization Following Portal Vein Embolization in Promoting Regeneration of Liver Volume and Function Before Right‐Sided Major Hepatectomy

Annals of Gastroenterological Surgery, EarlyView.
Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai, Kosuke Matsui, Hideyuki Matsushima, Hidekazu Yamamoto, Gozo Kiguchi, Hisashi Kosaka, Van Khanh Nguyen, Yasuhiro Ueno, Shuji Kariya, Masaki Kaibori   +9 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Distinct Gut Microbiota Profiles Associated with Advanced Hepatocellular Carcinoma in a Thai Cohort: A 16S rRNA Sequencing Study. [PDF]

Cancers (Basel)
Charoenthanadhol T, Phetcharaburanin J, Bubpamala T, Sookprasert A, Chindaprasirt J, Sanlung T, Watcharenwong P, Putraveephong S, Wirasorn K.   +8 more
europepmc   +1 more source

Natural Polyphenol–Metal Supramolecular Nanocomplex for Ferroptosis Activation in Chemoresistant Hepatocellular Carcinoma

Aggregate, EarlyView.
This study presents a supramolecular nanocomplex assembled from a natural polyphenol and Cu(II) that enables cascade glutathione (GSH) depletion through synthesis inhibition, redox cycling, and Michael addition. The system induces dual cytoplasmic and mitochondrial ferroptosis in cisplatin‐resistant hepatocellular carcinoma (HCC), reverses drug ...
Yan Qin, Jialong Fan, Yi Zhang, Wei Yang, Jianzhong Cao, Bin Liu, Qing He   +6 more
wiley   +1 more source

Attacking the public health crisis of hepatocellular carcinoma at its roots

Hepatology, EarlyView., 2022
Abstract As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.
Hannah M. Lee, Steven D. Lidofsky, Tamar H. Taddei, Lisa J. Townshend‐Bulson   +3 more
wiley   +1 more source

Author Correction: hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p. [PDF]

Sci Rep
Huang S, Liu K, Xu Y, Wang H, Fu S, Wu J.   +5 more
europepmc   +1 more source