Results 31 to 40 of about 289,858 (341)
A Novel Hepadnavirus is Associated with Chronic Hepatitis and Hepatocellular Carcinoma in Cats
In 2015, over 850,000 people died from chronic hepatitis and hepatocellular carcinoma (HCC) caused by hepatitis B virus (HBV). A novel hepatitis B-like virus has recently been identified in domestic cats.
Patricia A. Pesavento+7 more
doaj +1 more source
Stanford researchers have shown that NOTCH activation can protect against hepatocellular carcinoma, adding to new findings that argue for ramping up NOTCH signaling to treat some cancers. The team plans to tease out the mechanisms by which NOTCH promotes some cancers and has antitumor effects in others.
openaire +2 more sources
Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells [PDF]
The aetiology of human fibrolamellar hepatocellular carcinomas (hFL-HCCs), cancers occurring increasingly in children to young adults, is poorly understood.
ALVARO, Domenico+13 more
core +2 more sources
We have previously conducted a phase I trial to test the efficacy of a glypican-3 (GPC3) peptide vaccine in patients with advanced hepatocellular carcinoma (HCC); however, its immunological mechanism of action remains unclear.
Nobuhiro Tsuchiya+7 more
doaj +1 more source
Mitochondrial Dysfunction in the Transition from NASH to HCC
The liver constantly adapts to meet energy requirements of the whole body. Despite its remarkable adaptative capacity, prolonged exposure of liver cells to harmful environmental cues (such as diets rich in fat, sugar, and cholesterol) results in the ...
Mélissa Léveillé, Jennifer L. Estall
doaj +1 more source
Development and Validation of a New Prognostic System for Patients with Hepatocellular Carcinoma [PDF]
BACKGROUND: Prognostic assessment in patients with hepatocellular carcinoma (HCC) remains controversial. Using the Italian Liver Cancer (ITA.LI.CA) database as a training set, we sought to develop and validate a new prognostic system for patients with ...
Benvegnu', Luisa+28 more
core +4 more sources
Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. [PDF]
Hepatocellular carcinoma (HCC), is one of the most frequent human cancer and is characterized by a high mortality rate. The aggressiveness appears strictly related to the liver pathological background on which cancer develops.
Amicone, Laura, Marchetti, Alessandra
core +1 more source
In the era of transformative technologies, generative artificial intelligence (genAI) offers profound opportunities and challenges for education. This study explores the development and execution of an interactive workshop designed to equip educators ...
Benedikt Brünner+2 more
doaj +1 more source
EFFECT OF GROUNDWATER SALINITY LEVEL ON SOIL USING REMOTE SENSING AND GIS TECHNIQUES: CASE STUDY OF SOUTHWEST OF BASRA PROVINCE [PDF]
Groundwater salinity level is one of the most important considerations for monitoring soil degradation that threat some regions in the southwest of Basra Province, Iraq. The aim of this research is to assign the appropriate and effective image processing
MUSHTAK T. JABBAR+2 more
doaj
Focal adhesion kinase: Insight into molecular roles and functions in hepatocellular carcinoma [PDF]
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Due to the high incidence of post-operative recurrence after current treatments, the identification of new and more effective drugs is required.
Alisi, Anna+4 more
core +2 more sources