Virus-Like Particles and Nanoparticles for Vaccine Development against HCMV
Viruses, 2019 Human cytomegalovirus (HCMV) infects more than 70% of the human population worldwide. HCMV is responsible for high morbidity and mortality in immunocompromised patients and remains the leading viral cause of congenital birth defects. Despite considerable
Michela Perotti, Laurent Perez
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HCMV Antivirals and Strategies to Target the Latent Reservoir [PDF]
Viruses, 2021 Human cytomegalovirus (HCMV) is a ubiquitous human herpesvirus. In healthy people, primary infection is generally asymptomatic, and the virus can go on to establish lifelong latency in cells of the myeloid lineage.
Marianne R Perera, M. Wills, J. Sinclair
semanticscholar +5 more sources
Distinct expression profile of HCMV encoded miRNAs in plasma from oral lichen planus patients
Journal of Translational Medicine, 2017 Background Oral lichen planus (OLP) is a T cell-mediated autoimmune disease. The aetiology and molecular mechanisms of OLP remain unclear. Human cytomegalovirus (HCMV) infection is a causal factor in the development of various diseases, but the clinical ...
Meng Ding +7 more
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Human cytomegalovirus infection induces L1 expression through UL38-dependent mTOR-KAP1 pathway. [PDF]
PLoS ONEHuman cytomegalovirus (HCMV) and LINE-1 (L1) can co-inhabit a common host and closely interact with each other within a single cell. We have previously shown that HCMV exploits this opportunistic interaction by upregulating L1 expression that promotes ...
Sehong Park, Jiseok Jeong, Kwangseog Ahn
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Human Cytomegalovirus Encoded miR-US25-1-5p Attenuates CD147/EMMPRIN-Mediated Early Antiviral Response. [PDF]
, 2017 Cellular receptor-mediated signaling pathways play critical roles during the initial immune response to Human Cytomegalovirus (HCMV) infection.
Chen, Huizi +6 more
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Frontiers in Cellular and Infection Microbiology, 2023 Cancer is one of the leading causes of death worldwide. Human cytomegalovirus (HCMV), a well-studied herpesvirus, has been implicated in malignancies derived from breast, colorectal muscle, brain, and other cancers.
Chuan Yu +5 more
semanticscholar +1 more source
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization
Science Advances, 2022 Human cytomegalovirus (HCMV) represents the viral leading cause of congenital birth defects and uses the gH/gL/UL128-130-131A complex (Pentamer) to enter different cell types, including epithelial and endothelial cells.
M. Kschonsak +15 more
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Human cytomegalovirus is present in the odontogenic epithelium of ameloblastoma
Journal of Oral Microbiology, 2021 Background: The factor behind the activation of the remnant odontogenic tissues and development of odontogenic cysts and tumors is poorly understood.This study aimed to investigate the presence of human cytomegalovirus (HCMV) in dentigerous cyst (DC ...
Mohammed Amjed Alsaegh +3 more
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Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation [PDF]
, 2014 NKG2D plays a major role in controlling immune responses through the regulation of natural killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct ligands (the MHC Class I polypeptide-related sequences (MIC) A ...
A Dolan +98 more
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Serological Study of Human Cytomegalovirus (CMV) in Diabetic Patients in Kirkuk Governorate [PDF]
Kirkuk Journal of Science, 2015 The aim of this study was to know the relationship between the human cytomegalovirus and diabetes mellitus through detection of human cytomegalovirus (HCMV) infection in diabetic patients in Kirkuk governorate by screening of anti-human cytomegalovirus
Najat Abdul-Kadir Zaman
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