Results 21 to 30 of about 46,134 (291)

Molecular Variations in Glycoprotein B of Asian Human Cytomegalovirus: Potential Impact on Virus Entry and Immune Evasion in Ocular Diseases. [PDF]

J Med Virol
ABSTRACT Human cytomegalovirus (HCMV)‐associated ocular diseases have gained increasing attention due to a recent rise in cases diagnosed in Asia. A glycoprotein encoded by the virus UL55 gene, glycoprotein B (gB), is essential for viral entry and a primary target for naturally‐produced antibodies and vaccine development.
Lestari T, Yawata N, Gonzalez G, Miyadera H, Motooka D, Imamura Y, Oki H, Mori Y, Shirane M, Khor SS, Omae Y, Shimada M, Windy DA, Nakano S, Tsutsui H, Kuramoto S, Fukui C, Nakamura R, Yamana S, Kaburaki T, Mashimo H, Takase H, Yanai R, Hasegawa E, Shibata K, Yawata M, Tokunaga K, Ohguro N, Sonoda KH.   +28 more
europepmc   +2 more sources

Human cytomegalovirus is present in the odontogenic epithelium of ameloblastoma

Journal of Oral Microbiology, 2021
Background: The factor behind the activation of the remnant odontogenic tissues and development of odontogenic cysts and tumors is poorly understood.This study aimed to investigate the presence of human cytomegalovirus (HCMV) in dentigerous cyst (DC ...
Mohammed Amjed Alsaegh, Sudhir Rama Varma, Alaa Muayad Altaie, Shengrong Zhu   +3 more
doaj   +1 more source

Suppressive effects of pterostilbene on human cytomegalovirus (HCMV) infection and HCMV-induced cellular senescence [PDF]

Virology Journal, 2022
Abstract Background Human cytomegalovirus (HCMV), a member of the β-herpesvirus family, causes the establishment of a latent infection that persists throughout the life of the host and can be reactivated when immunity is weakened.
Sanying Wang, Xuqiang Zhou, Xinyue He, Shushu Ma, Chuan Sun, Jing Zhang, Xiaogang Xu, Weihua Jin, Jin Yan, Ping Lin, Genxiang Mao   +10 more
openalex   +4 more sources

Identification of Proteins in Human Cytomegalovirus (HCMV) Particles: the HCMV Proteome [PDF]

Journal of Virology, 2004
ABSTRACT Human cytomegalovirus (HCMV), a member of the herpesvirus family, is a large complex enveloped virus composed of both viral and cellular gene products. While the sequence of the HCMV genome has been known for over a decade, the full set of viral and cellular proteins that compose the HCMV virion are unknown.
Susan M, Varnum, Daniel N, Streblow, Matthew E, Monroe, Patricia, Smith, Kenneth J, Auberry, Ljiljana, Pasa-Tolic, Dai, Wang, David G, Camp, Karin, Rodland, Steven, Wiley, William, Britt, Thomas, Shenk, Richard D, Smith, Jay A, Nelson   +13 more
openaire   +3 more sources

Serological Study of Human Cytomegalovirus (CMV) in Diabetic Patients in Kirkuk Governorate [PDF]

Kirkuk Journal of Science, 2015
The aim of this study was to know the relationship between the human cytomegalovirus and diabetes mellitus through detection of human cytomegalovirus (HCMV) infection in diabetic patients in Kirkuk governorate by screening of anti-human cytomegalovirus
Najat Abdul-Kadir Zaman
doaj   +1 more source

Human Cytomegalovirus Infection Induces High Expression of Prolactin and Prolactin Receptors in Ovarian Cancer

Biology, 2020
One of the potential biomarkers for ovarian cancer patients is high serum level of prolactin (PRL), which is a growth factor that may promote tumor cell growth.
Afsar Rahbar, Amira AlKharusi, Helena Costa, Mattia Russel Pantalone, Ourania N. Kostopoulou, Huanhuan L. Cui, Joseph Carlsson, Angelique Flöter Rådestad, Cecilia Söderberg-Naucler, Gunnar Norstedt   +9 more
doaj   +1 more source

Bystander CD4+ T cells infiltrate human tumors and are phenotypically distinct

OncoImmunology, 2022
Tumor-specific T cells likely underpin effective immune checkpoint-blockade therapies. Yet, most studies focus on Treg cells and CD8+ tumor-infiltrating lymphocytes (TILs).
Shamin Li, Summer Zhuang, Antja Heit, Si-Lin Koo, Aaron C. Tan, I-Ting Chow, William W. Kwok, Iain Beehuat Tan, Daniel S.W. Tan, Yannick Simoni, Evan W. Newell   +10 more
doaj   +1 more source

Small Molecules—Prospective Novel HCMV Inhibitors [PDF]

Viruses, 2021
Human cytomegalovirus (HCMV), a member of the betaherpesvirinae, can cause life-threatening diseases. HCMV is globally widespread, with a seroprevalence in adults varying from 50 to 100%. HCMV infection is rarely of significant consequence in immunocompetent individuals.
Elke Bogner, Anna Egorova, Vadim Makarov
openaire   +3 more sources

Early immune surveillance to predict cytomegalovirus outcomes after allogeneic hematopoietic stem cell transplantation

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundThere is no method of predicting human cytomegalovirus (HCMV) outcomes in allogeneic hematopoietic stem cell transplant recipients clinically, leading in some cases to excessive or insufficient antiviral therapy.
Jintao Xia, Xuejie Li, Genyong Gui, Jian Wu, Shengnan Gong, Yuxin Shang, Jun Fan   +6 more
doaj   +1 more source

Molecular characterization of HCMV‐specific immune responses: Parallels between CD8⁺ T cells, CD4⁺ T cells, and NK cells [PDF]

European Journal of Immunology, 2015
Felipe A. Vieira Braga, Kirsten M. L. Hertoghs, René A. W. van Lier, Klaas P. J. M. van Gisbergen   +3 more
openalex   +2 more sources