Results 31 to 40 of about 44,631 (298)

Altered serum human cytomegalovirus microRNA levels are common and closely associated with the inflammatory status in patients with fever

Frontiers in Immunology, 2022
BackgroundFever has a complicated etiology, and diagnosing its causative factor is clinically challenging. Human cytomegalovirus (HCMV) infection causes various diseases.
Cheng Wang, Cheng Wang, Yunhua Zhu, Yunhua Zhu, Penglu Chen, Penglu Chen, Chen Wang, Wanqing Zhou, Wanqing Zhou, Cuiping Zhang, Jing Wang, Xi Chen, Meng Ding, Meng Ding, Chunni Zhang, Chunni Zhang, Jun-Jun Wang, Chen-Yu Zhang, Chen-Yu Zhang   +18 more
doaj   +1 more source

Tuning the Orchestra: HCMV vs. Innate Immunity

Frontiers in Microbiology, 2020
Understanding how the innate immune system keeps human cytomegalovirus (HCMV) in check has recently become a critical issue in light of the global clinical burden of HCMV infection in newborns and immunodeficient patients. Innate immunity constitutes the
Valentina Dell’Oste, Matteo Biolatti, Ganna Galitska, G. Griffante, F. Gugliesi, Selina Pasquero, A. Zingoni, C. Cerboni, M. De Andrea   +8 more
semanticscholar   +1 more source

A Molecular Implicatory Propositioning Roles for Human Cytomegalovirus and P16 Gene Expression in Oral Squamous Cellular Carcinogenesis

Journal of Pure and Applied Microbiology, 2019
Oral carcinogenesis is a multi-step process, affecting predominantly elderly males with a long history of smoking and alcohol drinking while the role of infectious agents in its progression has not been fully identified.
Hayat Ghaith Sachit, Taghreed F. Almahbobi, Zahraa Muhsen M. Ali, Saad Hasan Mohammed Ali, Shakir H. Mohammed Al-Alwany   +4 more
doaj   +1 more source

Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation

Clinical & Translational Immunology, 2023
Objectives Human cytomegalovirus (HCMV) reactivation is the leading viral complication after allogeneic haematopoietic stem cell transplantation (allo‐HSCT).
Lauren Stern, Helen M McGuire, Selmir Avdic, Emily Blyth, David Gottlieb, Ellis Patrick, Allison Abendroth, Barry Slobedman   +7 more
doaj   +1 more source

Development of a Human Cytomegalovirus (HCMV)-Based Therapeutic Cancer Vaccine Uncovers a Previously Unsuspected Viral Block of MHC Class I Antigen Presentation [PDF]

, 2019
Human cytomegalovirus (HCMV) induces a uniquely high frequency of virus-specific effector/memory CD8+ T-cells, a phenomenon termed “memory inflation”.
Abate, Ahmed, Alexandrov, Alexandrov, Arnon, Avdic, Beyranvand Nejad, Brown, Brown, Browne, Chang, Chu, Cloughesy, Cobbs, Dasari, Dekhtiarenko, Del Val, Desjardins, Doisne, Dos Santos, Draper, Duhen, Dziurzynski, Engels, Fiallos, Filley, Fruh, Galluzzi, Gilbert, Gorzer, Harkins, Heemskerk, Howland, Jarry, Johnson, Jutz, Jutz, Kern, Klenerman, Korn, Kotenko, Lauvau, Le, Leisegang, Lim, Lockridge, Locy, Louveau, Lucas, Luo, Malouli, Martikainen, Mitchell, Mocarski, Nair, Neefjes, Odeberg, Overwijk, Pardieck, Polyzoidis, Potter, Prins, Pule, Raftery, Raftery, Raftery, Raftery, Rahman, Ratzinger, Reap, Reardon, Reed, Ressing, Riegler, Rizvi, Rosato, Rosskopf, Sampaio, Sampson, Sandalova, Schempp, Scheper, Schmolke, Schneider, Schonrich, Schub, Sckisel, Shah, Simoni, Sinzger, Soroceanu, Soroceanu, Strang, Stupp, Sturm, Sugawara, Sylwester, Thomas, Tischer, Tran, Trgovcich, Tumeh, van der Burg, van Willigen, Varnum, Vlahovic, Wen, Wills, Yan, Zhao   +109 more
core   +1 more source

Priming of NK cell anti-viral effector mechanisms by direct recognition of Human Cytomegalovirus

Frontiers in Immunology, 2013
NK cells play an important role in the defense against viral infections. Activation of resting NK cells is tightly controlled by the balance of surface inhibitory and activating receptors and aided by cytokines released by accessory cells along the anti ...
Aura eMuntasell, Marcel eCosta-Garcia, Andrea eVera, Noemi eMarina-Garcia, Carsten J Kirschning, Miguel eLópez-Botet, Miguel eLópez-Botet   +6 more
doaj   +1 more source

The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]

, 1985
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael, Calendar, R., Dorsch-Häsler, Karoline, Fleckenstein, Bernhard, Gold, L., Jahn, Gerhard, Rüger, Rüdiger, Schaffner, Walter, Stoerker, Jay, Weber, Frank   +9 more
core   +1 more source

Infection of human cytomegalovirus in cultured human gingival tissue. [PDF]

, 2006
BackgroundHuman cytomegalovirus (HCMV) infection in the oral cavity plays an important role in its horizontal transmission and in causing viral-associated oral diseases such as gingivitis.
Chu, Alice, Hai, Rong, Li, Hongjian, Liu, Fenyong, Rider, Paul, Umamoto, Sean   +5 more
core   +3 more sources

A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]

, 1985
A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael, Dorsch-Häsler, Karoline, Fleckenstein, Bernhard, Jahn, Gerhard, Schaffner, Walter, Weber, Frank   +5 more
core   +1 more source

Activating KIRs and NKG2C in viral infections: towards NK cell memory?

Frontiers in Immunology, 2015
Natural Killer cells are important players in the immune defence against viral infections. The contribution of activating Killer Immunoglobulin-like Receptors (KIRs) and CD94/NKG2C in regulating anti-viral responses has recently emerged.
Mariella eDella Chiesa, Simona eSivori, Simona eCarlomagno, Lorenzo eMoretta, Alessandro eMoretta   +4 more
doaj   +1 more source