Results 21 to 30 of about 4,460,555 (293)
Antioxidants, 2019 Indirubin-3′-monoxime (I3M) exhibits anti-proliferative activity in various cancer cells; however, its anti-cancer mechanism remains incompletely elucidated.
Matharage Gayani Dilshara +7 more
doaj +1 more source
Investigation of fusion gene expression in HCT116 cells
Oncology Letters, 2017 Colon cancer is the most common type of gastrointestinal cancer. A number of specific and sensitive biomarkers facilitate the diagnosis and monitoring of patients with colon cancer. Fusion genes are typically identified in cancer and a majority of the newly identified fusion genes are oncogenic in nature.
Yanmei, Zhang +3 more
openaire +3 more sources
Human HCT116 cells internalize bacterial OMVs.
, 2022 Confocal microscopy imaging of human HCT116 cells stained with cell tracker CMTPX (in red) and incubated with bacterial OMVs labelled with PKH67 (in green) for 2 h (A) or 18 h (B). Nuclei were stained with DAPI (in blue).
Marine Lambert (340966) +7 more
core +1 more source
Induction of p53-Dependent Apoptosis by Prostaglandin A2
Biomolecules, 2020 Prostaglandin (PG) A2, one of cyclopentenone PGs, is known to induce activation of apoptosis in various cancer cells. Although PGA2 has been reported to cause activation of apoptosis by altering the expression of apoptosis-related genes, the role of p53,
Su-Been Lee +4 more
doaj +1 more source
FEBS Open Bio, 2023 5‐Fluorouracil (5‐FU) is widely used for colorectal cancer (CRC) treatment; however, continuous treatment of CRC cells with 5‐FU can result in acquired resistance, and the underlying mechanism of 5‐FU resistance remains unclear. We previously established
Chinatsu Kurasaka +4 more
doaj +1 more source
Unacetylated CDC42 K153 promotes the invasion ability of HCT116 cells.
, 2023 (A) Percentage of HCT116 cells in the different stages of the cell cycle after stimulation with (STM) or without (UI) S. Typhimurium. Cell cycle stage distribution was determined by flow cytometry analysis after PI staining.
Jian-Hui Li (2570410) +8 more
core +1 more source
Entrainment of superoxide rhythm by menadione in HCT116 colon cancer cells [PDF]
Scientific Reports, 2019 AbstractReactive oxygen species (ROS) are primary effectors of cytotoxicity induced by many anti-cancer drugs. Rhythms in the pseudo-steady-state (PSS) levels of particular intracellular ROS in cancer cells and their relevance to drug effectiveness are unknown thus far.
Uma Kizhuveetil +5 more
openaire +2 more sources
Flavanones inhibit the clonogenicity of HCT116 cololectal cancer cells
International Journal of Molecular Medicine, 2011 Naringenin has been shown to display various biological effects such as antioxidant, anticancer, anti-inflammatory, and antiviral activities. Taxifolin inhibits the production of lipopolysaccharide-induced prostaglandin E, and fustin suppresses the activity of acetylcholinesterase. They all belong to flavanone
Yoonkyung, Woo +5 more
openaire +3 more sources
Marine Drugs, 2023 Human colorectal cancer (CRC) is a recurrent, deadly malignant tumour with a high incidence. The incidence of CRC is of increasing alarm in highly developed countries, as well as in middle to low-income countries, posing a significant global health ...
Blessing Mabate +3 more
doaj +1 more source
The hedgehog/Gli-1 signaling pathways is involved in the inhibitory effect of resveratrol on human colorectal cancer HCT116 cells [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): The study aimed to investigate the effects of resveratrol on colorectal cancer HCT116 cells, including cell viability, apoptosis, and migration, and the partial mechanisms focused on hedgehog/gli-1 signaling pathways. Materials and Methods:
Zhou Du +7 more
doaj +1 more source