Results 31 to 40 of about 4,460,555 (293)

williamhconrad/HCT116-decitabine-hub: Decitabine Hub repository under CC0 license

open access: yes, 2020
Bisulfite PCR of select differentially methylated regions in HCT116 ...
williamhconrad
core   +1 more source

Acss2/Cbp/HIF-2α interactions in HCT116 cells.

open access: yes, 2023
(A) Acetylation detected by immunoblotting (IB) of ectopic HIF-2α in HIF-2α knockdown HCT116 cells rescued with wild-type (K3) or arginine-lysine substituted mutant (R3) HIF-2α (upper panel), or of endogenous HIF-2α in Acss2 knockdown HCT116 cells ...
Shelby D. Melton (14709834)   +6 more
core   +1 more source

Basic Studies on Radioimmunotargeting of CD133-Positive HCT116 Cancer Stem Cells [PDF]

open access: yesMolecular Imaging, 2012
As cancer stem cells (CSCs) are postulated to play critical roles in cancer development, including metastasis and recurrence, CSC imaging would provide valuable information for cancer treatment and lead to CSC-targeted therapy. To assess the possibility of in vivo CSC targeting, we conducted basic studies on radioimmunotargeting of
Zhao-Hui Jin   +6 more
openaire   +3 more sources

The impact of p53 on the early stage replication of retrovirus

open access: yesVirology Journal, 2017
Background The function of p53 in cancer biology has been studied extensively, but its role in anti-retrovirus infection has been elusive for many years. The restriction of retrovirus early stage replication by p53 was investigated in this study.
Michaela Kinnetz   +4 more
doaj   +1 more source

6-Shogaol Inhibits the Cell Migration of Colon Cancer by Suppressing the EMT Process Through the IKKβ/NF-κB/Snail Pathway

open access: yesIntegrative Cancer Therapies, 2023
6-Shogaol from ginger has anti-inflammatory, anti-oxidation and anti-cancer effects. Aim of the Study: To study the effects and possible mechanisms of 6-Shogaol on inhibiting the migration of colon cancer cells Caco2 and HCT116 and prove the effects on ...
Min Chen PhD   +6 more
doaj   +1 more source

Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells [PDF]

open access: yesBiomolecules & Therapeutics, 2016
Columbianadin (CBN), a natural coumarin from Angelica decursiva (Umbelliferae), is known to have various biological activities including anti-inflammatory and anti-cancer effects. In this study, the anti-proliferative mechanism of actions mediated by CBN was investigated in HCT-116 human colon cancer cells.
Kang, Ji In   +3 more
openaire   +2 more sources

CTRP1 Knockout Attenuates Tumor Progression in A549 and HCT116 Cancer Cells

open access: yesCancers, 2022
C1q and TNF-related 1 (C1QTNF1/CTRP1) is an adiponectin-associated protein belonging to the C1q/TNF-related protein family. Recent studies have shown that the C1q and TNF-related protein (CTRP) family is involved in cancer progression; however, the specific role of CTRP1 in tumor progression has not yet been elucidated.
Rackhyun Park   +5 more
openaire   +2 more sources

Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-κB and Src protein kinase signaling pathways.

open access: yesPLoS ONE, 2013
ObjectiveDevelopment of treatment resistance and adverse toxicity associated with classical chemotherapeutic agents highlights the need for safer and effective therapeutic approaches.
Mehdi Shakibaei   +5 more
doaj   +1 more source

miR193a-5p Mediated ZNF746 and c-Myc Signaling Axis Is Critically Involved in Morusin Induced Apoptosis in Colorectal Cancer Cells

open access: yesCells, 2021
Novel target therapy is on the spotlight for effective cancer therapy. Hence, in the present study, the underlying apoptotic mechanism of Morusin was explored in association with miR193a-5p mediated ZNF746/c-Myc signaling axis in colorectal cancer cells (
Woon-Yi Park   +7 more
doaj   +1 more source

Influence of microRNA-34a on proliferation, invasion and metastasis of HCT116 cells

open access: yesMolecular Medicine Reports, 2016
The aim of the present study was to investigate the role of microRNA (miR)‑34a expression in the proliferation, invasion and metastasis of colon cancer and its underlying mechanisms. HCT116 cells were cultured in high‑sugar Dulbecco's modified Eagle's medium (DMEM) containing 10% fetal bovine serum and 1000 U/ml penicillin‑streptomycin.
Chunyan, Li   +6 more
openaire   +3 more sources

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