Results 1 to 10 of about 2,132 (113)
Effect of extracellular vesicles derived from either blood or dental pulp stem cells on human dental pulp stem cells: an in vitro study [PDF]
BDJ OpenObjective This study aimed to determine and compare the possible proliferative and differentiative effects of extracellular vesicles (EVs) derived from human dental pulp stem cells (hDPSCs-EVs) and human blood plasma (hBP-EVs) on hDPSCs as an in-vitro ...
Mona A. Amer +3 more
doaj +2 more sources
Sal-hDPSCs Transplantation Alleviates Hypoxic-Ischaemic Ferroptosis in Neonatal Rats Via the FSP1-CoQ10 Axis [PDF]
International Dental JournalObjective: To investigate the therapeutic effects and mechanisms of salidroside-pretreated human dental pulp stem cells (Sal-hDPSCs) on hypoxic-ischaemic brain damage (HIBD) in neonatal rats, providing a scientific basis for clinical application of ...
Kang Xu +7 more
doaj +2 more sources
Mitochondrial transplant activates Ca2+/TFAP2A to promote hDPSCs-mediated dentin-pulp regeneration [PDF]
Stem Cell Research & TherapyBackground The dentin-pulp complex (DPC) is composed of the odontoblastic layer and associated stromal components. It serves key functions in immunological homeostasis and tissue regeneration of dental tissues.
Peimeng Zhan +7 more
doaj +2 more sources
Scientific ReportsDental pulp stem cells (DPSCs) show potential for treating neurodegenerative and traumatic diseases due to their neural crest origin. Melatonin (MT), an endogenous neurohormone with well-documented anti-inflammatory and antioxidant properties, has shown ...
Zolikha Golipoor +2 more
exaly +2 more sources
Regenerative capacity of human dental pulp stem cells versus their exosomes on surgically induced submandibular gland defects in rats [PDF]
BMC Oral HealthBackground Surgical excision of salivary gland (SG) tumors frequently results in glandular tissue loss and long-term functional impairment. Human dental pulp stem cells (hDPSCs) and their derived Exosomes (hDPSCs-Exos) have emerged as promising ...
Basma A Hammad +4 more
doaj +2 more sources
Secreted Peptidome Profiling of Human Dental Pulp Stem Cells–Conditioned Medium During Odontogenic Differentiation [PDF]
International Dental JournalIntroduction and Aims: Odontogenic differentiation of human dental pulp stem cells (hDPSCs) is critical for pulp repair. This study aims to characterise the secretory peptidome of human dental pulp stem cells (hDPSCs) during odontogenic differentiation ...
Yanhua Huang +6 more
doaj +2 more sources
Immunomodulatory properties of human dental pulp stromal cells: the role of IL-6/JAK/STAT3 pathway and PD-L1 [PDF]
Frontiers in ImmunologyIntroductionHuman Dental Pulp Stromal Cells (hDPSCs) of neural-ectodermal origin hold immunomodulatory properties which make them a source for MSC-based therapies for the treatment of autoimmune diseases.MethodsIn this study hDPSCs were exposed to ...
Rosanna Di Tinco +13 more
doaj +2 more sources
Biomedical Papers, 2022 Aims. By measuring the extent of cytokines secreted by human dental pulp stem cells (hDPSCs) from passages 2 through 10, the optimal passage of hDPSCs was determined.
Ming Yan +8 more
doaj +1 more source
Journal of Dental Sciences, 2023 Background/purpose: Naringenin, a naturally occurring flavanone in citrus fruits, regulates bone formation by bone marrow-derived mesenchymal stem cells. The purpose of this study was to characterize the effects of naringenin on some biological behaviors
Yeon Kim +7 more
doaj +1 more source
Journal of Dental Sciences, 2023 Background/purpose: Human dental pulp stem cells (hDPSCs) possess excellent proliferative and osteogenic differentiation potentials. This study aimed to elucidate the role of lysophosphatidic acid (LPA) signaling in the proliferation and osteogenic ...
Soon Chul Heo +8 more
doaj +1 more source