Results 31 to 40 of about 3,065 (190)

Ultrastructure of hDPSCs cultured on SA.

, 2019
hDPSCs were cultured on scaffolds for up to 6 weeks and processed for transmission electron microscopy (TEM). dt, dentin tubule; id, intertubular dentin; pd, peritubular dentin; cp, cellular process; a, actin filaments; g, glycogen; n, nucleus; sv ...
Amando Peydró (6685856), José Javier Martín-de-Llano (6685850), Carmen Carda (300876), Manuel Mata (300872), Santiago Peydró (6685853)   +4 more
core   +3 more sources

Human dental pulp stem cells (hDPSCs) promote the lipofibroblast transition in the early stage of a fibro-inflammatory process [PDF]

, 2023
Introduction: In autoimmune diseases, particularly in systemic sclerosis and chronic periaortitis, a strict correlation between chronic inflammation and fibrosis exists. Since the currently used drugs prove mostly effective in suppressing inflammation, a
Laura Bertoni, Sena, Paola, Gianluca Carnevale, Orciani, Monia, Bertacchini, Jessika, Paola Sena, Carlo Salvarani, Elisa Pignatti, Jessika Bertacchini, Di Tinco, Rosanna, Bertani, Giulia, Monia Orciani, Bertoni, Laura, Giulia Orlandi, Orlandi, Giulia, Giulia Bertani, Pignatti, Elisa, Alessandra Pisciotta, Rosanna Di Tinco, Salvarani, Carlo, Carnevale, Gianluca, Pisciotta, Alessandra   +21 more
core   +1 more source

An Investigation about Gene Modules Associated with hDPSC Differentiation for Adolescents

Stem Cells International, 2019
Dental pulp stem cells (DPSCs) have the property of self-renewal and multidirectional differentiation so that they have the potential for future regenerative therapy of various diseases. The latest breakthrough in the biology of stem cells and the development of regenerative biology provides an effective strategy for regenerative therapy.
Wenjing Xu, Jianqiang Li, Juan Li, Ji-Jiang Yang, Qing Wang, Bo Liu, Weiliang Qiu   +6 more
openaire   +3 more sources

Blockade of PD-L1/PD-1 signaling promotes osteo-/odontogenic differentiation through Ras activation

International Journal of Oral Science, 2022
The programmed cell death ligand 1 (PD-L1) and its receptor programmed cell death 1 (PD-1) deliver inhibitory signals to regulate immunological tolerance during immune-mediated diseases.
So Mi Jeon, Je Sun Lim, Su Hwan Park, Hyung Joon Kim, Hyung-Ryong Kim, Jong-Ho Lee   +5 more
doaj   +1 more source

TAT&RGD Peptide-Modified Naringin-Loaded Lipid Nanoparticles Promote the Osteogenic Differentiation of Human Dental Pulp Stem Cells

International Journal of Nanomedicine, 2022
Chun-Yan Zheng,1,* Xiao-Yang Chu,2,* Chun-Yan Gao,1 Hua-Ying Hu,3 Xin He,1 Xu Chen,1 Kai Yang,4 Dong-Liang Zhang1 1Department of Orthodontics, Beijing Stomatological Hospital, Capital Medical University School of Stomatology, Capital Medical ...
Zheng CY, Chu XY, Gao CY, Hu HY, He X, Chen X, Yang K, Zhang DL   +7 more
doaj  

TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory microenvironment

Stem Cell Research & Therapy, 2022
Background Inflammatory microenvironment promotes odontoblastic differentiation in human dental pulp stem cells (hDPSCs), but the regulatory mechanisms remain unclear.
Wen Kang, Yiwen Wang, Jiaying Li, Weige Xie, Dan Zhao, Li Wu, Hongwei Wang, Sijing Xie   +7 more
doaj   +1 more source

Different expression patterns of inflammatory cytokines induced by lipopolysaccharides from Escherichia coli or Porphyromonas gingivalis in human dental pulp stem cells

BMC Oral Health, 2022
Background Lipopolysaccharide (LPS) is one of the leading causes of pulpitis. The differences in establishing an in vitro pulpitis model by using different lipopolysaccharides (LPSs) are unknown.
Chunhua Lan, Shuai Chen, Shan Jiang, Huaxiang Lei, Zhiyu Cai, Xiaojing Huang   +5 more
doaj   +1 more source

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars. [PDF]

Int Endod J
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Abdalla MM, Rajasekar V, Ahmed H, Huang M, Yiu CKY.   +4 more
europepmc   +2 more sources

A novel hypoxic lncRNA, HRL-SC, promotes the proliferation and migration of human dental pulp stem cells through the PI3K/AKT signaling pathway

Stem Cell Research & Therapy, 2022
Background Human dental pulp stem cells (hDPSCs) are critical for pulp generation. hDPSCs proliferate faster under hypoxia, but the mechanism by which long noncoding RNA (lncRNA) regulates this process is not fully understood.
Junkai Zeng, Ming Chen, Yeqing Yang, Buling Wu   +3 more
doaj   +1 more source

Effect of lncRNA TUG1 on osteogenic/odontogenic differentiation of human dental pulp stem cells

口腔疾病防治, 2022
Objective To explore the effects of long noncoding-RNA (lncRNA) taurine upregulated gene 1 (TUG1) on the proliferation and osteogenic/odontoblast differentiation of human dental pulp stem cells (hDPSCs). Methods hDPSCs were isolated and cultured.
JIANG Yaxin, ZHANG Hua, SUN Linghan, LI Shiting, FENG Hao   +4 more
doaj   +1 more source