Results 51 to 60 of about 3,065 (190)

Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K+ stimulation

Biophysics and Physicobiology, 2020
As human-origin cells, human dental pulp stem cells (hDPSCs) are thought to be potentially useful for biological and medical experiments. They are easily obtained from lost primary teeth or extracted wisdom teeth, and they are mesenchymal stem cells that
Yuki Kogo, Chiaki Seto, Yuki Totani, Mai Mochizuki, Taka Nakahara, Kotaro Oka, Tohru Yoshioka, Etsuro Ito   +7 more
doaj   +1 more source

Biological Characteristics of Fluorescent Superparamagnetic Iron Oxide Labeled Human Dental Pulp Stem Cells

Stem Cells International, 2017
Tracking transplanted stem cells is necessary to clarify cellular properties and improve transplantation success. In this study, we investigate the effects of fluorescent superparamagnetic iron oxide particles (SPIO) (Molday ION Rhodamine-B™, MIRB) on ...
Liang Ma, Ming-wei Li, Yu Bai, Hui-hui Guo, Sheng-chao Wang, Qing Yu   +5 more
doaj   +1 more source

Effect of Biodentine on Odonto/Osteogenic Differentiation of Human Dental Pulp Stem Cells

Bioengineering, 2022
This study aims to compare the biological characteristics of human dental pulp stem cells (hDPSCs) isolated from different-aged populations and examine the effects of Biodentine on proliferation and odonto/osteogenic differentiation of hDPSCs isolated ...
Xuerong Wang, Yixin Cai, Min Zhang, Junchen Xu, Chengfei Zhang, Jin Li   +5 more
doaj   +1 more source

EVL Promotes Osteo-/Odontogenic Differentiation of Dental Pulp Stem Cells via Activating JNK Signaling Pathway

Stem Cells International, 2023
Objective. Human dental pulp stem cells (hDPSCs) were recognized as a suitable and promising source of stem cells in dental pulp regeneration. However, the mechanism by which hDPSCs differentiation into osteo-/odontogenic lineage remains unclear.
Kangrui Zeng, Qiongyi Kang, Yutong Li, Weiping Li, Qing Cheng, Wenwei Xia   +5 more
doaj   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Enhancing osteogenic potential of hDPSCs by resveratrol through reducing oxidative stress via the Sirt1/Nrf2 pathway [PDF]

, 2022
Context The osteogenic potential of the human dental pulp stromal cells (hDPSCs) was reduced in the state of oxidative stress. Resveratrol (RSV) possesses numerous biological properties, including osteogenic potential, growth-promoting and antioxidant ...
Man, K, Yang, XB, Li, R, Zhang, J, Xuebin B. Yang, Jingying Zhang, Kenny Man, Rui Li   +7 more
core   +1 more source

Human dental pulp stem cell response to a novel photoinitiator for resin‐based dental materials

European Journal of Oral Sciences, EarlyView.
Abstract This study aimed to assess the cytotoxicity of a novel polymerization initiator, tert‐butyl (tert‐butyldimethylsilyl) glyoxylate (DKSi), and its effect on cytokine release by human dental pulp stem cells (hDPSCs), compared with camphorquinone (CQ) and diphenyl(2,4,6‐trimethylbenzoyl)phosphine oxide (TPO).
Giulia Gamero Pizzanelli, Matheus Kury, Jean‐Pierre Salomon, Jacques Lalevée, Denise Carleto Andia, Adriano F. Lima   +5 more
wiley   +1 more source

Patch-clamp electrophysiology analysis of neuronal differentiated SH-SY5Y and hDPSCs.

, 2022
(A) Mean I-V relationship of INa in SH-SY5Y (control, n = 23; ATRA, n = 25; ATRA→BDNF, n = 21). (B) Mean I-V relationship for IKss in SH-SY5Y (control, n = 22; ATRA, n = 18; ATRA→BDNF, n = 23). (C) Mean cell capacitance in SH-SY5Y (control, n = 45; ATRA,
Paul R. Cooper (4909843), Arwa A. Al-Maswary (14059542), Molly O’Reilly (6734201), Ben A. Scheven (14059548), Andrew P. Holmes (1456315), A. Damien Walmsley (14059545)   +5 more
core   +1 more source

R‐Loops Mediated Odontogenic Differentiation of hDPSCs by Activating the cGAS‐STING Pathway Under Inflammatory Microenvironment

Oral Diseases, EarlyView.
ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang, Yiqing Wang, Yating Miao, Zhipu Luo, Lin Niu, Ruirui Liu   +5 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, Volume 13, Issue 57, 14 October 2026.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source