Results 61 to 70 of about 3,065 (190)

Cell morphology of hDPSCs cultured on SB.

, 2019
hDPSCs were cultured on scaffolds for 6 weeks and processed for light microscopy. Samples were embedded in paraffin, cut into sections, and subjected to Masson’s trichrome staining (panel A) or immunohistochemistry for DSPP (panel B).
Amando Peydró (6685856), José Javier Martín-de-Llano (6685850), Carmen Carda (300876), Manuel Mata (300872), Santiago Peydró (6685853)   +4 more
core   +1 more source

NZ-GMP Approved Serum Improve hDPSC Osteogenic Commitment and Increase Angiogenic Factor Expression [PDF]

Frontiers in Physiology, 2016
Human dental pulp stem cells (hDPSCs), selected from the stromal-vascular fraction of dental pulp, are ecto-mesenchymal stem cells deriving from neural crests, successfully used in human bone tissue engineering. For their use in human therapy GMP procedures are required.
Spina, Anna, Montella, Roberta, Liccardo, Davide, De Rosa, Alfredo, Laino, Luigi, Mitsiadis, Thimios A., La Noce, Marcella   +6 more
openaire   +5 more sources

Mechanosensitive PIEZO1 Regulates Angiogenic Signaling in Human Dental Pulp Stem Cells

Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT Dental pulp stem cells (DPSCs) possess multilineage differentiation potential and contribute to dental pulp regeneration through odontoblast replacement and neovascularization. Although mechanosensitive ion channels such as PIEZO1 are known to regulate stem cell fate, their role in DPSC‐mediated angiogenesis under mechanical stress remains ...
Ai Orimoto, Chihiro Nakatomi, Chiaki Kitamura, Kentaro Ono   +3 more
wiley   +1 more source

Development of a Nano‐Hybrid Composite Using Bovine Hydroxyapatite and Montmorillonite for Endodontic Applications—An In Vitro Study

International Endodontic Journal, Volume 59, Issue 9, Page 1936-1953, September 2026.
ABSTRACT Aim Hydraulic calcium silicate cements are widely employed in endodontics due to their excellent biocompatibility, bioactivity, sealing ability, and remineralisation potential. However, currently used products such as mineral trioxide aggregate (MTA) exhibit several limitations, including discolouration, cost, and poor handling properties ...
P. A. A. S. Prasad Kumara, Paul R. Cooper, Peter Cathro, Henry F. Duncan, Maree Gould, George Dias, Jithendra Ratnayake   +6 more
wiley   +1 more source

Ultrastructure of hDPSCs cultured on SB.

, 2019
hDPSCs were cultured on scaffolds for 6 weeks and processed for TEM. r, rough endoplasmic reticulum; a, actin filaments; g, glycogen; sv, secretory vesicles; n, nuclei.
Amando Peydró (6685856), José Javier Martín-de-Llano (6685850), Carmen Carda (300876), Manuel Mata (300872), Santiago Peydró (6685853)   +4 more
core   +1 more source

EDA1 variants inhibit the odontogenic differentiation and proliferation of human dental pulp stem cells

BMC Oral Health
Background Variants of Ectodysplasin A1 (EDA1) regulate the proliferation, migration, and odontogenic differentiation of human dental pulp stem cells (hDPSCs).
Yulin Ding, Genqi Lu, Ya Zhao, Yi Zhang, Jing Zhang, Jingle Ma, Yunyun Yuan, Boyu Liu, Wei Liu, Wenjing Shen   +9 more
doaj   +1 more source

CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation

International Dental Journal, 2023
: Objectives: Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cell possessing self-renewal and multilineage differentiation capabilities. The dysfunction of DPSCs is related to the pathologic process of pulpitis.
Cuiwei Liang, Wenmiao Li, Qian Huang, Qitao Wen   +3 more
doaj   +1 more source

Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review

International Endodontic Journal, Volume 59, Issue 9, Page 1792-1803, September 2026.
ABSTRACT Introduction Regenerative endodontic procedures (REPs) have been widely used to manage a range of pulpal pathologies, particularly in immature permanent teeth. The development of bioactive calcium silicate–based materials has led to a paradigm shift in vital pulp therapy (VPT) and REPs.
Mahmoud Torabinejad, Neda Najafimakhsoos, George Bogen   +2 more
wiley   +1 more source

Evidence Mapping and Quality Assessment of Randomized Controlled Trials in Dental Traumatology

Dental Traumatology, Volume 42, Issue 4, Page 542-560, August 2026.
ABSTRACT Background/Aims This evidence mapping (EM) and quality assessment of randomized controlled trials (RCTs) in Dental Traumatology (DT) aimed to identify the RCTs, distribute them in different domains and subdomains, analyze their methodological characteristics, and assess their quality.
Nitesh Tewari, Garima Jhunjhunwala, Amritha Rajeswary, Morankar Rahul, Vijay Prakash Mathur   +4 more
wiley   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, Volume 13, Issue 41, 22 July 2026.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source