Results 71 to 80 of about 3,065 (190)

Biodentine Counteracts the Aging Process of Human Dental Pulp Stem Cells Through Wnt/β-Catenin Pathway

International Dental Journal
Objectives: This study aimed to evaluate the effects of Biodentine on human Dental Pulp Stem Cells (hDPSCs) proliferation and senescence and explore the underlying anti-aging mechanism. Methods: hDPSCs were isolated from two groups of patients aged 18 to
Qi Zhang, Shujie Cao, Min Zhang, Daming Wu, Chengfei Zhang, Jin Li   +5 more
doaj   +1 more source

LncRNA XIST facilitates the odontogenic differentiation of dental pulp stem cells via the FUS/ZBTB16 [PDF]

Journal of Applied Oral Science
Objective This study aims to explore the regulatory mechanism of long noncoding RNA X inactive specific transcript (lncRNA XIST) in the odontogenic differentiation of human dental pulp stem cells (hDPSCs).
Ruiqing CHENG, Honglei SUN, Xiaotong QIAO, Xuefang CHEN   +3 more
doaj   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, Volume 13, Issue 36, 29 June 2026.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Adenovirus-mediated transfer of hepatocyte growth factor gene to human dental pulp stem cells under good manufacturing practice improves their potential for periodontal regeneration in swine [PDF]

, 2015
Figure S1. Showing biological functions of hDPSCs and HGF-hDPSCs under GMP conditions. Representative phase-contrast microscopic photographs of hDPSCs after culturing for A 7 days (first passage) and B 18 days (fourth passage); the morphology is ...
Songlin Wang, Chu-Tse Wu (652664), Jingchao Hu (3542525), Yilin Xie, Jingchao Hu, Zhenhai Liu (2084866), Jingsong Wang (3542528), Hua Wang (13530), Zhipeng Fan, Zhipeng Fan (110971), Chunmei Zhang, Hua Wang, Yu Cao, Zhenhai Liu, Chu-Tse Wu, Yilin Xie (2349235), Songlin Wang (67512), Jingsong Wang, Yu Cao (274482), Chunmei Zhang (67508)   +19 more
core   +1 more source

Effect of C5a Receptor Antagonist on the Osteogenic Differentiation of Dental Pulp Stem Cells

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objective Complement component 5a (C5a) binding to its receptor (C5aR) can mediate pro‐inflammatory immune responses, which impairs osteogenic differentiation of dental pulp stem cells (DPSCs). The present study aimed to evaluate the regulatory effect of C5aR antagonist (W54011) on the osteogenic differentiation of DPSCs in an in vitro ...
Xiaohan Tan, Junlong Hu, Junhui Li, Zhuangying Chen, Xin Shi, Jie Liu, Mingyue Liu, Weiping Hu   +7 more
wiley   +1 more source

2,4-D causes oxidative stress induction and apoptosis in human dental pulp stem cells (hDPSCs)

2,4-Dicholorophenoxy acetic acid (2,4-D) is a worldwide used hormone herbicide. Human dental pulp stem cells (hDPSCs) as a potential source of mesenchymal stem cells provide a confident model system for the assessments of chemicals in vitro.
نیاپور, علی, محمودی نیا, سمیرا, مأذنی, محمد, قاسمی حمیدآبادی, هاتف   +3 more
core   +1 more source

Extracellular matrix secreted by hDPSCs cultured on SA.

, 2019
hDPSCs were cultured on scaffolds for 6 weeks and processed for light microscopy. Samples were embedded in paraffin, cut into sections, and subjected to Masson’s trichrome staining (panel A) or immunohistochemistry for dentin sialophosphoprotein (DSPP ...
Amando Peydró (6685856), José Javier Martín-de-Llano (6685850), Carmen Carda (300876), Manuel Mata (300872), Santiago Peydró (6685853)   +4 more
core   +1 more source

In Vitro Evaluation of Novel Calcium Silicate‐Based and Resin‐Modified Calcium Silicate Materials: Cytocompatibility and Mineralization Potential on Human Dental Pulp Stem Cells for Pulp Repair

Microscopy Research and Technique, Volume 89, Issue 6, Page 932-947, June 2026.
This study demonstrates that Biodentine XP exhibits superior cytocompatibility, promotes odontogenic differentiation, and enhances mineralization in human dental pulp stem cells, supporting its use in regenerative endodontics. Resin‐modified materials showed lower bioactivity, highlighting the importance of material composition in pulp therapy outcomes.
Francisco Javier Rodríguez‐Lozano, Nuria Pérez‐Guzmán, Paula García‐Rios, David García‐Bernal, Adrián Lozano, Sergio López‐García   +5 more
wiley   +1 more source

hDPSCs surface antigens expression and in vitro multilineage differentiation ability.

, 2012
A: Cytofluorimetric analysis of Stro-1, c-Kit and CD34 expression in hDPSCs cultured in FCS-medium and in HS-medium. Dot plots reporting SSC vs fluorescence are shown.
Francesca Beretti (117500), Tullia Maraldi (117508), Giacomo Bruzzesi (117521), Massimo Riccio (117494), Anto De Pol (117525), Lara Gibellini (117504), Gian Maria Cavallini (117512), Gianluca Carnevale (117495), Adriano Ferrari (117517), Alessandra Pisciotta (117491)   +9 more
core   +1 more source

Circ‐0030167/IGF2BP1 Induces Mitophagy‐Mediated Ferroptosis via HMOX1 mRNA Stabilization in Pancreatic Cancer

Cancer Science, Volume 117, Issue 5, Page 1362-1379, May 2026.
Our findings identify circ‐0030167/IGF2BP1/HMOX1 axis as a critical regulatory factor targeting mitochondria‐mediated ferroptosis, thereby presenting a novel therapeutic target for PC combination therapies. ABSTRACT Pancreatic cancer (PC) represents a highly aggressive malignancy characterized by a 5 year survival rate of less than 12%.
Qun Zhao, Xihao Yao, Jingjing Lu, Qiyang Chen, Zhiwei Wang, Xiaohong Li, Yuhua Lu   +6 more
wiley   +1 more source