Results 1 to 10 of about 198,685 (310)

Head and neck squamous cell carcinoma

Nature Reviews Disease Primers, 2020
Head and neck squamous cell carcinomas (HNSCCs) originate from the mucosal epithelium in the oral cavity, pharynx and larynx, and are caused by viral infection or carcinogen exposure.
Daniel E. Johnson, B. Burtness, C. Leemans, Vivian Wai Yan Lui, J. Bauman, Jennifer R. Grandis   +5 more
semanticscholar   +2 more sources

Pharmacological impact of microRNAs in head and neck squamous cell carcinoma: Prevailing insights on molecular pathways, diagnosis, and nanomedicine treatment

Frontiers in Pharmacology, 2023
Head and neck squamous cell carcinoma is a disease that most commonly produce tumours from the lining of the epithelial cells of the lips, larynx, nasopharynx, mouth, or oro-pharynx. It is one of the most deadly forms of cancer.
Bedanta Bhattacharjee, Ayesha Farhana Syeda, Damanbhalang Rynjah, Shalam M. Hussain, Shekhar Chandra Bora, Padmanath Pegu, Ram Kumar Sahu, Jiyauddin Khan   +7 more
doaj   +1 more source

Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma

Medical Science, 2023
Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies, involving the oral cavity, pharynx, hypopharynx, larynx, nasal cavity, and salivary glands, that together compose the seventh most common cancer diagnosis worldwide.
Adam Barsouk, J. Aluru, Prashanth Rawla, Kalyan Saginala, Alexander Barsouk   +4 more
semanticscholar   +1 more source

Early postoperative serum albumin levels as predictors of surgical outcomes in head and neck squamous cell carcinoma

Brazilian Journal of Otorhinolaryngology, 2022
Background: Malnutrition is a common issue in patients with head and neck squamous cell carcinoma and has a negative effect on surgical outcomes. Objective: We attempted to determine which malnutrition diagnostic variables can be used as predictors of ...
Tercio Guimarães Reis, Richard Alex Wesler Prudêncio da Silva, Eliane dos Santos Nascimento, José de Bessa, Júnior, Márcio Campos Oliveira, Antônio Sérgio Fava, Carlos Neutzling Lehn   +6 more
doaj   +1 more source

The identification of tumor antigens and immune subtypes based on the development of immunotherapies targeting head and neck squamous cell carcinomas resulting from periodontal disease

Frontiers in Oncology, 2023
Among cancer treatments, immunotherapy is considered a promising strategy. Nonetheless, only a small number of individuals with head and neck squamous cell carcinoma exhibit positive responses to immunotherapy.
Yangju Fu, Yongbo Zheng
doaj   +1 more source

Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression

Cancer Communications, 2022
Cancer cells selectively promote the translation of oncogenic transcripts to stimulate cancer progression. Although growing evidence has revealed that tRNA modifications and related genes participate in this process, their roles in head and neck squamous
Jie Chen, Kang Li, Jianwen Chen, Xiaochen Wang, Rongsong Ling, M. Cheng, Zhi Chen, Fangfang Chen, Qianting He, Shuaijie Li, Caihua Zhang, Yizhou Jiang, Qianming Chen, Anxun Wang, Demeng Chen   +14 more
semanticscholar   +1 more source

Tongue squamous cell carcinoma metastasis to percutaneous endoscopic gastrostomy site: A case report of an unusual cause of gastrointestinal bleeding

SAGE Open Medical Case Reports, 2023
Percutaneous endoscopic gastrostomy tubes are often placed in patients with head and neck malignancy for long-term nutritional support. Though rare, head and neck squamous cell carcinoma can metastasize to the percutaneous endoscopic gastrostomy tube ...
Hunza Chaudhry, Humzah Iqbal, Amitpaul Gill, Alakh Gulati, Juliana Yang   +4 more
doaj   +1 more source

Phase 1/2a, open‐label, multicenter study of RM‐1929 photoimmunotherapy in patients with locoregional, recurrent head and neck squamous cell carcinoma

Head and Neck, 2021
Recurrent head and neck squamous cell carcinoma (rHNSCC) represents a significant global health burden with an unmet medical need. In this study we determined the safety and efficacy of RM‐1929 photoimmunotherapy in patients with heavily pretreated ...
D. Cognetti, J. Johnson, J. Curry, S. Kochuparambil, D. McDonald, F. Mott, M. Fidler, K. Stenson, N. Vasan, M. Razaq, J. Campaña, P. Ha, G. Mann, Kosuke Ishida, M. García-Guzmán, M. Biel, A. Gillenwater   +16 more
semanticscholar   +1 more source

B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma

Nature Communications, 2021
Current immunotherapy paradigms aim to reinvigorate CD8+ T cells, but the contribution of humoral immunity to antitumor immunity remains understudied.
A. Ruffin, Anthony R. Cillo, T. Tabib, Angen Liu, Sayali S Onkar, S. Kunning, C. Lampenfeld, Huda I Atiya, I. Abécassis, Cornelius H. L. Kürten, Z. Qi, R. Soose, U. Duvvuri, Seungwon Kim, Steffi Oesterrich, R. Lafyatis, L. Coffman, R. Ferris, D. Vignali, T. Bruno   +19 more
semanticscholar   +1 more source

Better outcome for parotid versus neck metastasis of head and neck cutaneous squamous cell carcinoma: a new report on reemerging data

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: Regional metastases of cutaneous head and neck squamous cell carcinoma occur in approximately 5 % of cases, being the most important prognostic factor in survival, currently with no distinction between parotid and neck metastasis. Objective:
Fábio Muradás Girardi, Vivian Petersen Wagner, Manoela Domingues Martins, Aliende Lengler Abentroth, Luiz Alberto Hauth   +4 more
doaj   +1 more source