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Advanced Oropharyngeal Cancer Can Be Easily Missed During Esophagogastroduodenoscopy [PDF]

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2017
The case of an elderly man with an advanced oropharyngeal cancer that was missed during esophagogastroduodenoscopy is described. He was referred for endoscopic resection of superficial esophageal squamous cell neoplasms.
Kenta Hamada   +3 more
doaj   +3 more sources

Head and neck squamous cell carcinoma [PDF]

open access: yesNature Reviews Disease Primers, 2020
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx and are known collectively as head and neck squamous cell carcinoma (HNSCC). Oral cavity and larynx cancers are generally associated with tobacco consumption, alcohol abuse or both, whereas pharynx cancers are increasingly attributed to infection ...
Johnson, Daniel E   +5 more
  +12 more sources

Pharmacological impact of microRNAs in head and neck squamous cell carcinoma: Prevailing insights on molecular pathways, diagnosis, and nanomedicine treatment

open access: yesFrontiers in Pharmacology, 2023
Head and neck squamous cell carcinoma is a disease that most commonly produce tumours from the lining of the epithelial cells of the lips, larynx, nasopharynx, mouth, or oro-pharynx. It is one of the most deadly forms of cancer.
Bedanta Bhattacharjee   +7 more
doaj   +1 more source

Early postoperative serum albumin levels as predictors of surgical outcomes in head and neck squamous cell carcinoma

open access: yesBrazilian Journal of Otorhinolaryngology, 2022
Background: Malnutrition is a common issue in patients with head and neck squamous cell carcinoma and has a negative effect on surgical outcomes. Objective: We attempted to determine which malnutrition diagnostic variables can be used as predictors of ...
Tercio Guimarães Reis   +6 more
doaj   +1 more source

Head and Neck Squamous Cell Carcinoma: Epigenetic Landscape [PDF]

open access: yesDiagnostics, 2020
Head and neck squamous carcinoma (HNSCC) constitutes the sixth most prevalent cancer worldwide. The molecular pathogenesis of HNSCC includes disorders in cell cycle, intercellular signaling, proliferation, squamous cell differentiation and apoptosis. In addition to the genetic mutations, changes in HNSCC are also characterized by the accumulation of ...
Kamila Romanowska   +4 more
openaire   +3 more sources

The identification of tumor antigens and immune subtypes based on the development of immunotherapies targeting head and neck squamous cell carcinomas resulting from periodontal disease

open access: yesFrontiers in Oncology, 2023
Among cancer treatments, immunotherapy is considered a promising strategy. Nonetheless, only a small number of individuals with head and neck squamous cell carcinoma exhibit positive responses to immunotherapy.
Yangju Fu, Yongbo Zheng
doaj   +1 more source

Tongue squamous cell carcinoma metastasis to percutaneous endoscopic gastrostomy site: A case report of an unusual cause of gastrointestinal bleeding

open access: yesSAGE Open Medical Case Reports, 2023
Percutaneous endoscopic gastrostomy tubes are often placed in patients with head and neck malignancy for long-term nutritional support. Though rare, head and neck squamous cell carcinoma can metastasize to the percutaneous endoscopic gastrostomy tube ...
Hunza Chaudhry   +4 more
doaj   +1 more source

PKM2 Modulation in Head and Neck Squamous Cell Carcinoma [PDF]

open access: yesInternational Journal of Molecular Sciences, 2022
The enzyme pyruvate kinase M2 (PKM2) plays a major role in the switch of tumor cells from oxidative phosphorylation to aerobic glycolysis, one of the hallmarks of cancer. Different allosteric inhibitors or activators and several posttranslational modifications regulate its activity. Head and neck squamous cell carcinoma (HNSCC) is a common disease with
Verena Boschert   +4 more
openaire   +3 more sources

Immunotherapy for Head and Neck Squamous Cell Carcinoma [PDF]

open access: yesCurrent Oral Health Reports, 2016
Head and neck squamous cell carcinoma has been found to be an immunosuppressive malignancy, with many defects in the host immune system contributing to the progression of disease. A greater understanding of these defects has lead to the identification and investigation of new therapeutic strategies, targeting immune system dysfunction in an effort to ...
Rebecca C, Hoesli, Jeffrey S, Moyer
openaire   +5 more sources

Immunotherapy for Head and Neck Squamous Cell Carcinoma [PDF]

open access: yesCurrent Oncology Reports, 2018
Discussion of current strategies targeting the immune system related to solid tumors with emphasis on head and neck squamous cell carcinoma (HNSCC).This review will outline the current challenges with immunotherapy and future goals for treatment using these agents.Agents targeting immune checkpoint receptors (IR) such as program death 1 (PD1) have been
Moskovitz, Jessica   +2 more
openaire   +2 more sources

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