Results 101 to 110 of about 382,120 (258)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ethical Infrastructure and Successful Handling of Workplace Bullying
Nordic Journal of Working Life Studies, 2017 Antecedents and consequences of workplace bullying are well documented. However, the mea- sures taken against workplace bullying, and the effectiveness of such measures, have received less attention.
Kari Einarsen +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Reach and Recruitment of Microentrepreneurs: Lessons from a Finnish Health Promotion Intervention
Nordic Journal of Working Life Studies, 2022 Even though entrepreneurial work is stressful, health promotion interventions are seldom targeted at entrepreneurs, and we know little about how to reach and recruit this hard-to-reach group to such studies.
Jaana-Piia Mäkiniemi +10 more
doaj
Young People’s Attitudes to Attractive Work, During and After Upper Secondary School
Nordic Journal of Working Life Studies, 2017 Attractive work has been defined as a job position which an individual wants, where the employee experiences job stability and where employee identification and dedication are fostered.
Ing-Marie Andersson +3 more
doaj +1 more source
How Do Practitioners Create Inclusive Environments For Children With Chronic Health Conditions? An Exploratory Case Study [PDF]
, 2014 The concept of inclusion within the English education system is often taken for granted. There are a number of factors that can impact on inclusive practice and this demands careful exploration.
Musgrave, Jackie
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Health and wellbeing in a deep plan office space [PDF]
, 2008 This research tracks public sector employees as they move from a 1960s office building into a purpose-built, environmentally sound, office accommodation.
Brown, Guy, Capper, Graham, Holmes, John
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Beyond safety to wellbeing: How local authorities can mitigate the mental health risks of living in houses in multiple occupation [PDF]
, 2012 The regulation of houses in multiple occupation (HMOs) by local authorities focuses on ensuring the physical safety of occupants through adequate standards of building quality, safety provision and management suitability.
Barratt, C, Kitcher, C, Stewart, J
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