Results 91 to 100 of about 91,653 (266)

Measurement of healthy ageing

Age and Ageing, 2023
Gichu, Muthoni, Harwood, Rowan H
openaire   +2 more sources

Insights into salt perception and cognitive impairment among middle-aged and older adults: a scoping review

BMC Public Health
Background A decline in taste sensitivity from aging leads people with a higher salt threshold to frequently add more salt to their food, which attributed to decreased cognitive efficiency.
Azira Sazali, Suzana Shahar, Hasnah Haron, Nor Fadilah Rajab, Fatin Hanani Mazri, Theng Choon Ooi, Nurul Fatin Malek Rivan   +6 more
doaj   +1 more source

From Mixing methods to the logic(s) of inquiry: taking a fresh look at developing mixed design studies

Health Psychology and Behavioral Medicine, 2018
Objective: This invited paper offers an innovative framework for mixed methods research design. Method: We propose the adoption of the Model of Disciplined Inquiry, a five-component model that focuses on the research question(s) rather than the type(s ...
Rachel L. Shaw, David R. Hiles, Karen West, Carol Holland, Holly Gwyther   +4 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Machine learning predicts lifespan and suggests underlying causes of death in aging C. elegans

Communications Biology
Aging leads to age-related pathology that causes death, and genes affect lifespan by determining such pathology. Here we investigate how age-related pathology mediates the effect of genetic and environmental interventions on lifespan in C.
Carina C. Kern, Petru Manescu, Matt Cuffaro, Catherine Au, Aihan Zhang, Hongyuan Wang, Ann F. Gilliat, Sophie van Schelt, Marina Ezcurra, David Gems   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Limited health literacy increases the likelihood of cognitive frailty among older adults

BMC Geriatrics
Background Cognitive frailty is a dual geriatric syndrome that is preventable with lifestyle changes. Lifestyle changes are influenced by literacy level.
Jamilah Mohammad Hanipah, Arimi Fitri Mat Ludin, Devinder Kaur Ajit Singh, Ponnusamy Subramaniam, Suzana Shahar   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source