Results 111 to 120 of about 107,517 (316)
BMC Public HealthObjective In this study, we examined the longitudinal trajectories of falls and physical activity statuses among older adults and identified factors associated with state transitions.
Theng Choon Ooi +3 more
doaj +1 more source
Healthy aging in the Americas [PDF]
Revista Panamericana de Salud Pública, 2021 Jarbas Barbosa da Silva Jr. +2 more
openaire +3 more sources
Discover the beauty of plant foods for your healthy ageing
, 2013 Globally, cardiovascular disease (CVD) and cancer are the leading causes of disability and death in older age. With the increase in average life expectancy, it is important to understand how lifestyle factors can help to reduce our risk of chronic ...
Jin, Yannan
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Drugs & AgingAbstract Appropriate drug treatment can enhance the likelihood of experiencing healthy aging and maintaining functional ability up to very late in life. Strong evidence exists that overall drugs can help prevent and manage diseases. However, such evidence is mostly available from studies that are not representative of older people and do not ...
Sarah N. Hilmer +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Machine learning predicts lifespan and suggests underlying causes of death in aging C. elegans
Communications BiologyAging leads to age-related pathology that causes death, and genes affect lifespan by determining such pathology. Here we investigate how age-related pathology mediates the effect of genetic and environmental interventions on lifespan in C.
Carina C. Kern +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Limited health literacy increases the likelihood of cognitive frailty among older adults
BMC GeriatricsBackground Cognitive frailty is a dual geriatric syndrome that is preventable with lifestyle changes. Lifestyle changes are influenced by literacy level.
Jamilah Mohammad Hanipah +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source