Results 101 to 110 of about 91,653 (266)

Healthy human ageing

New Biotechnology, 2008
Udgivelsesdato ...
openaire   +2 more sources

Colony level fitness analysis identifies a trade-off between population growth rate and dauer yield in Caenorhabditis elegans

BMC Ecology and Evolution
Background In the evolution from unicellular to multicellular life forms, natural selection favored reduced cell proliferation and even programmed cell death if this increased organismal fitness.
Hannah Chapman, Kuei Ching Hsiung, Isadora Rawlinson, Evgeniy R. Galimov, David Gems   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Drugs and Healthy Aging

Drugs & Aging
Abstract Appropriate drug treatment can enhance the likelihood of experiencing healthy aging and maintaining functional ability up to very late in life. Strong evidence exists that overall drugs can help prevent and manage diseases. However, such evidence is mostly available from studies that are not representative of older people and do not ...
Sarah N. Hilmer, Luigi Ferrucci, Antonio Cherubini   +2 more
openaire   +2 more sources

Translational perspectives on neurophysiological responses and mechanisms in blood flow restriction exercise

Experimental Physiology
Maintaining corticospinal tract function is crucial for voluntary movement. Exercise using high external loads/intensities is a promising intervention to promote adaptations to the corticospinal tract and improve physical function; however, such loads ...
Kai T. Fox, Luke Hughes, Brendan R. Scott, Paul S. R. Goods, Shaun YM. Teo, Ann‐Maree Vallence   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Healthy aging [PDF]

BMJ, 1997
openaire   +2 more sources

Vaccination and healthy aging

Expert Review of Vaccines, 2010
The aging process in humans is associated with a decrease in immune function (immunosenescence) and an increase in comorbid disorders. When combined with environmental factors this can lead to an increased risk and severity of infectious diseases. Diseases in older adults (>/=70 years) tend to be more severe and have a greater impact on health outcomes
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Healthy aging in the Americas [PDF]

Revista Panamericana de Salud Pública, 2021
Jarbas Barbosa da Silva Jr., John W. Rowe, Jose Ricardo Jauregui   +2 more
openaire   +3 more sources