Results 101 to 110 of about 107,517 (316)

Towards salutogenichealth promotion : organizing healthy ageing programs at the local level

, 2011
Als gevolg van landelijke wetgeving, zoals de Wet Publieke Gezondheid (WPG) en de Wet Maatschappelijke Ondersteuning (WMO), hebben gemeenten meer verantwoordelijkheden gekregen ten aanzien van hun oudere populatie.
Lezwijn, J.
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

ß-adrenergic-like signalling engages CrebB in Drosophila gut to promote female longevity

Nature Communications
Adrenergic signalling is heavily implicated in human age-related disease and yet the potential for this neuroendocrine signalling pathway to modulate ageing has received little attention.
Ahmed F. Sumit, Ben Whitehead, Ilgaz Özyeşil, Dunxin Shen, Shajahan Anver, Lazaros C. Foukas, Nazif Alic   +6 more
doaj   +1 more source

From Mixing methods to the logic(s) of inquiry: taking a fresh look at developing mixed design studies

Health Psychology and Behavioral Medicine, 2018
Objective: This invited paper offers an innovative framework for mixed methods research design. Method: We propose the adoption of the Model of Disciplined Inquiry, a five-component model that focuses on the research question(s) rather than the type(s ...
Rachel L. Shaw, David R. Hiles, Karen West, Carol Holland, Holly Gwyther   +4 more
doaj   +1 more source

Ageing, plasticity, and cognitive reserve in connectionist networks [PDF]

, 2008
Neurocomputational modeling has suggested that a range of mechanisms can lead to reductions in functional plasticity across development (Thomas & Johnson, 2006).
Thomas, Michael S.C., Michael S C Thomas
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Strategisch Fonds project Citizen Science for Healthy Lifestyle (2019-2022):eindrapportage [PDF]

, 2022
Het strategisch project Citizen Science for a Healthy Lifestyle is gestart op 1 november 2019. Het project had als doel: kennis, ervaring, scholing en internationalisering op het thema Citizen Science for Healthy Lifestyle bevorderen.
Tuinier, Kris, Jepkema, Nikki, van der Lucht, Fons, Korevaar, E.L., Beenen, Paul, van Holland, Berry, de Jong, Johan, Schuling, Rhoda   +7 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Insights into salt perception and cognitive impairment among middle-aged and older adults: a scoping review

BMC Public Health
Background A decline in taste sensitivity from aging leads people with a higher salt threshold to frequently add more salt to their food, which attributed to decreased cognitive efficiency.
Azira Sazali, Suzana Shahar, Hasnah Haron, Nor Fadilah Rajab, Fatin Hanani Mazri, Theng Choon Ooi, Nurul Fatin Malek Rivan   +6 more
doaj   +1 more source

Healthy Ageing In Scotland: Pilot Survey Report [PDF]

, 2017
Like most developed countries, Scotland has an ageing population. Currently, around 40% of its residents, some 2 million people, are aged 50+. Scotland will face many policy challenges associated with ageing over the next few decades, including how to ...

core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source