Results 101 to 110 of about 339,619 (303)

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego, Kellee Parker, William C. Thomsen, James B. Ford, Mallorie B. Heneghan, David Spencer Mangum, Jennifer L. McNeer, Luke D. Maese, Claire E. F. Miller, Richard Lemons, Taumoha Ghosh   +10 more
wiley   +1 more source

From Mixing methods to the logic(s) of inquiry: taking a fresh look at developing mixed design studies

Health Psychology and Behavioral Medicine, 2018
Objective: This invited paper offers an innovative framework for mixed methods research design. Method: We propose the adoption of the Model of Disciplined Inquiry, a five-component model that focuses on the research question(s) rather than the type(s ...
Rachel L. Shaw, David R. Hiles, Karen West, Carol Holland, Holly Gwyther   +4 more
doaj   +1 more source

Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing [PDF]

, 2013
Gastrointestinal disorders, including chronic constipation, faecal impaction and incontinence, are a major cause of morbidity in the ...
Colyer, Frances, Davies, Heather, Gamage, Prasanna, Ranson, Richard N., Saffrey, M.Jill, Yeoman, Mark   +5 more
core  

The effects of inspiratory muscle training in older adults [PDF]

, 2015
Purpose: Declining inspiratory muscle function and structure and systemic low-level inflammation and oxidative stress may contribute to morbidity and mortality during normal ageing.
Aznar-Lain, Belman, Borg, Bowling, Brooks, Bruunsgaard, Carey, Davis, DEAN E. MILLS, Dennis, Downey, Enright, Falaschetti, Febbraio, Freedman, Garcia-Rio, GRAHAM R. SHARPE, Greig, Ho, Huang, Huang, Illi, Jensen, Johnson, Johnson, Kharraz, Kregel, Kumar, Kyle, MICHAEL A. JOHNSON, Miller, Mills, Mills, Murphy, Phillips, Polkey, Ramirez-Sarmiento, Robertson, Romer, Romer, Takahashi, Tidball, Troosters, Washburn, Watsford, WILLIAM H. T. SMITH, Wolsk, YVONNE A. BARNETT   +47 more
core   +2 more sources

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source

Insights into salt perception and cognitive impairment among middle-aged and older adults: a scoping review

BMC Public Health
Background A decline in taste sensitivity from aging leads people with a higher salt threshold to frequently add more salt to their food, which attributed to decreased cognitive efficiency.
Azira Sazali, Suzana Shahar, Hasnah Haron, Nor Fadilah Rajab, Fatin Hanani Mazri, Theng Choon Ooi, Nurul Fatin Malek Rivan   +6 more
doaj   +1 more source

They're not doing bad for their age: ageing, leisure and active living. [PDF]

, 2004
The article focuses on the life of elderly people. The majority of older people are fit and well, live independently and are actively engaged in their community.
Grant, Bevan C.
core   +1 more source

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition [PDF]

, 2015
Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic understanding of the impact of aging on the intake, digestion, and absorption of nutrients is still lacking.
Bordoni, Alessandra, Dupont, Didier, Gille, Doreen, Kachal, Josefa, Peyron, Marie-Agnès, Pinto, Paula, Rémond, Didier., Santos, Claudia Nunes Dos, Shahar, Danit R., Tomás-Cobos, Lidia, Vergères, Guy, Walther, Barbara   +11 more
core   +4 more sources

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Dynamic transitions in falls and physical activity among older adults in Malaysia: a longitudinal multi-state analysis

BMC Public Health
Objective In this study, we examined the longitudinal trajectories of falls and physical activity statuses among older adults and identified factors associated with state transitions.
Theng Choon Ooi, Nurul Fatin Malek Rivan, Suzana Shahar, Devinder Kaur Ajit Singh   +3 more
doaj   +1 more source