Results 51 to 60 of about 338,464 (302)

Tissue-specific transcriptome profiling of Drosophila reveals roles for GATA transcription factors in longevity by dietary restriction

open access: yesnpj Aging and Mechanisms of Disease, 2018
Author summary Ageing human populations present a huge societal challenge, providing motivation to find ways to improve health in old age. Dietary restriction (DR), is one way to improve late-life health of animals from worms to mammals, and perhaps ...
Adam J. Dobson   +6 more
doaj   +1 more source

Physical capability and the advantages and disadvantages of ageing : Perceptions of older age by men and women in two British cohorts [PDF]

open access: yes, 2012
In an increasingly ageing society, its older members are receiving considerable political and policy attention. However, much remains to be learnt about public perceptions of older age, particularly the views and experiences of older individuals ...
Elliott, Jane   +3 more
core   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale   +6 more
wiley   +1 more source

Two forms of death in ageing Caenorhabditis elegans

open access: yesNature Communications, 2017
Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that are ...
Yuan Zhao   +12 more
doaj   +1 more source

Healthy human ageing

open access: yesNew Biotechnology, 2008
Udgivelsesdato ...
openaire   +2 more sources

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small   +3 more
wiley   +1 more source

The Economics of Healthy Ageing in China [PDF]

open access: yes, 2016
Healthy ageing is a challenge for many countries with significant shares of elderly people. Literature refers to China's ageing population as a ticking time bomb which paradoxically is both a challenge and an opportunity for the country.
Heshmati, Almas
core  

Nutrition, diet and immunosenescence [PDF]

open access: yes, 2013
Ageing is characterized by immunosenescence and the progressive decline in immunity in association with an increased frequency of infections and chronic disease.
Agrawal   +217 more
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus   +6 more
wiley   +1 more source

An innovative linked Electronic Health Record derived data ecosystem for understanding the complexities of health and ageing.

open access: yesInternational Journal of Population Data Science
Objective We describe the creation of an Electronic Health Record (EHR) derived linked data platform within the Australian National Centre for Healthy Ageing (NCHA).
Nadine Andrew   +7 more
doaj   +1 more source

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