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Healthy Aging as Disease? [PDF]
Frontiers in Aging Neuroscience, 2011 In the scientific and popular literature recently there has been a widespread call for classifying normal aging as a disease, a condition that can be “manipulated, treated, and delayed” (Gems, 2010; Kelland, 2010). The main argument given by supporters of this suggestion is that grant-awarding bodies would be more likely to fund research into how, when,
openaire +3 more sources
Stable Isotope-Labeled Lipidomics to Unravel the Heterogeneous Development Lipotoxicity
Molecules, 2018 Non-alcoholic fatty liver disease (NAFLD) as a global health problem has clinical manifestations ranging from simple non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH), cirrhosis, and cancer.
Lu-Min Shih +5 more
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Frontiers in Human Neuroscience, 2021 Substantial evidence indicates that cognitive training can be efficacious for older adults, but findings regarding training-related brain plasticity have been mixed and vary depending on the imaging modality.
Ania Mikos +5 more
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Socioeconomic Status and Access to Healthcare: Interrelated Drivers for Healthy Aging
Frontiers in Public Health, 2020 The rapid growth of the global aging population has raised attention to the health and healthcare needs of older adults. The purpose of this mini-review is to: (1) elucidate the complex factors affecting the relationship between chronological age, socio ...
D. McMaughan +2 more
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Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging
Cells, 2021 Aging is a fundamental biological process accompanied by a general decline in tissue function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive impairment or dementia, will become a growing public health issue.
Mengdi Yu +7 more
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Contributions of Dickkopf‐1 to Obesity‐Induced Bone Loss and Marrow Adiposity
JBMR Plus, 2020 Low bone strength in overweight individuals is a significant medical problem. One important determinant of mesenchymal stem cell fate into osteoblasts or adipocytes is the Wnt signaling pathway.
Juliane Colditz +3 more
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Brain Shape Changes Associated With Cerebral Atrophy in Healthy Aging and Alzheimer’s Disease
Frontiers of Mechanical Engineering, 2021 Both healthy and pathological brain aging are characterized by various degrees of cognitive decline that strongly correlate with morphological changes referred to as cerebral atrophy.
Yana Blinkouskaya, Johannes Weickenmeier
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Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men
Frontiers in Physiology, 2017 Introduction/Purpose: A number of studies have investigated the effect of training with a moderate exercise dose (3–6 h/weekly) on the inflammatory profile in blood, and the data are inconsistent.
Ronni E. Sahl +10 more
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Cells, 2021 7-Ketocholesterol (7KCh) is a major oxidized cholesterol product abundant in lipoprotein deposits and atherosclerotic plaques. Our previous study has shown that 7KCh accumulates in erythrocytes of heart failure patients, and further investigation ...
Mei-Ling Cheng +6 more
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Aging, longevity, and healthy aging: the public health approach
Aging Clinical and Experimental ResearchPopulation aging is one of the most significant global demographic changes of the 21st century, driven by increased life expectancy and declining fertility rates.
V. Gianfredi +5 more
semanticscholar +1 more source