Results 71 to 80 of about 11,242,010 (306)

Patient Activation in Childhood, Adolescent, and Young Adult Cancer Survivors: Current Insights and Implications for Survivorship Care—A Systematic Review From the e‐QuoL Project

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Patient activation—encompassing knowledge, confidence, and skills in managing individual's health—is a cornerstone of person‐centered care. However, its significance among childhood, adolescent, and young adult cancer survivors (CAYACS) remains unexplored. This article examines the application of the 13‐item Patient Activation Measure (
Charlotte Demoor‐Goldschmidt, Anne Maas, Gisela Michel, Amandine Bertrand, Kristen E. T. Thornton, Martine Bellanger, Anna‐Liesa Filbert, Desiree Grabow, Monica Muraca, Katharina Roser, Sara Oberti, Jelena Roganovic, Hanne Cathrine Lie   +12 more
wiley   +1 more source

Melatonin and healthy aging.

Vitamins and hormones, 2021
Preservation of a robust circadian rhythmicity (particulsarly of the sleep/wake cycle), a proper nutrition and adequate physical exercise are key elements for healthy aging. Aging comes along with circadian alteration, e.g.
D. Cardinali
semanticscholar   +1 more source

Utility of Computed Tomography Surveillance of Asymptomatic Infection in Children and Young Adults Before Allogeneic Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Asymptomatic infection poses a significant risk for children undergoing hematopoietic stem cell transplantation (HSCT). Pre‐transplant surveillance computed tomography (CT) is commonly used to identify occult infection, though its diagnostic yield remains uncertain.
Tyler Obermark, Pradipta Debnath, Rama S. Ayyala, Lara A. Danziger‐Isakov, Jane Koo, Kasiani C. Myers, William R. Otto, Aki Tanimoto, Andrew T. Trout, Cara E. Morin   +9 more
wiley   +1 more source

The Prevention Research Centers Healthy Aging Research Network

Preventing Chronic Disease, 2005
BackgroundThe Prevention Research Centers Healthy Aging Research Network (PRC–HAN), funded by the Centers for Disease Control and Prevention’s (CDC’s) Healthy Aging program, was created in 2001 to help develop partnerships and create a research agenda ...
The Healthy Aging Research Network Writing Group
doaj  

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase

iScience, 2022
Summary: Most tumor cells reactivate telomerase to ensure unlimited proliferation, whereas the expression of human telomerase reverse transcriptase (hTERT) is tightly regulated and rate-limiting for telomerase activity maintenance.
Zhifen Zhou, Yujing Li, Huimin Xu, Xiaowei Xie, Zibin He, Song Lin, Ruofei Li, Shouheng Jin, Jun Cui, Hai Hu, Feng Liu, Su Wu, Wenbin Ma, Zhou Songyang   +13 more
doaj   +1 more source

Anti-Inflammatory Properties of Diet: Role in Healthy Aging

Biomedicines, 2021
Inflammation is a physiological process involved in the defenses of the body and the repair of tissues. It is acutely activated by infections, trauma, toxins, or allergic reactions.
Kristine Stromsnes, A. G. Correas, J. Lehmann, J. Gambini, G. Olaso-González   +4 more
semanticscholar   +1 more source

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia, Giulia Reggiani, Elizabeth J. Maran, Maria Elisa Delle Fave, Ilaria Baido, Anna Chiara Frigo, Maria Paola Boaro, Raffaella Colombatti   +7 more
wiley   +1 more source

Unraveling the independent role of METTL3 in m6A modification and tumor progression in esophageal squamous cell carcinoma

Scientific Reports
METTL3 and METTL14 are traditionally posited to assemble the m6A methyltransferase complex in a stoichiometric 1:1 ratio, modulating mRNA fate via m6A modifications. Nevertheless, recent investigations reveal inconsistent expression levels and prognostic
Bin Du, Pu Wang, Lingyu Wei, Kai Qin, Zhen Pei, Jinping Zheng, Jia Wang   +6 more
doaj   +1 more source

Understanding the Role of Oxidative Stress in Platelet Alterations and Thrombosis Risk among Frail Older Adults

Biomedicines
Frailty and cardiovascular diseases are increasingly prevalent in aging populations, sharing common pathological mechanisms, such as oxidative stress. The evidence shows that these factors predispose frail individuals to cardiovascular diseases but also ...
Diego Arauna, Simón Navarrete, Cecilia Albala, Sergio Wehinger, Rafael Pizarro-Mena, Iván Palomo, Eduardo Fuentes   +6 more
doaj   +1 more source

The German version of the Mini Suffering State Examination (MSSE) for people with advanced dementia living in nursing homes

BMC Geriatrics, 2022
Background The Mini Suffering State Examination (MSSE) has been explicitly recommended to assess suffering in dementia patients. This study aimed to develop a German version of the MSSE and assess its psychometric properties involving people with ...
Naomi Zumstein, Keiko Yamada, Stefanie Eicher, Nathan Theill, Heike Geschwindner, Henrike Wolf, Florian Riese   +6 more
doaj   +1 more source