Results 41 to 50 of about 132,211,819 (268)

Peristaltic on-chip pump for tunable media circulation and whole blood perfusion in PDMS-free organ-on-chip and Organ-Disc systems

open access: yes, 2022
S.3963-3978Organ-on-chip (OoC) systems have become a promising tool for personalized medicine and drug development with advantages over conventional animal models and cell assays.
Rogal, Julia   +8 more
core   +1 more source

Design of vocieprint recognition system based on CNN-LSTM neural network

open access: yesDianzi Jishu Yingyong, 2021
For warning of cardiovascular disease,in order to early detect the change of heart and lung voice representing the signs of danger,the vocieprint recognition system based on CNN-LSTM is designed.
Mu Junjie, Yao Gang, Sun Tao
doaj   +1 more source

The tooth on-a-chip: a microphysiologic model system mimicking the biologic interface of the tooth with biomaterials

open access: yes, 2020
The tooth has a unique configuration with respect to biomaterials that are used for its treatment. Cells inside of the dental pulp interface indirectly with biomaterials via a calcified permeable membrane, formed by the dentin matrix and several ...
Bertassoni, Luiz E.   +7 more
core   +1 more source

WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue [PDF]

open access: yes, 2022
S.1645-1654Organ-on-a-chip systems possess a promising future as drug screening assays and as testbeds for disease modeling in the context of both single-organ systems and multi-organ-chips.
Zushin, P.J.H.   +8 more
core   +2 more sources

Organ-on-a-Chip and Lab-on-a-Chip Technologies in Cardiac Tissue Engineering

open access: yesBiomimetics
Microfluidic technologies have ushered in a new era in cardiac tissue engineering, providing more predictive in vitro models compared to two-dimensional culture studies. This review examines Organ-on-a-Chip (OoC) and Lab-on-a-Chip (LoC) platforms, with a
Daniele Marazzi   +3 more
doaj   +1 more source

Continuous contractile force and electrical signal recordings of 3D cardiac tissue utilizing conductive hydrogel pillars on a chip

open access: yesMaterials Today Bio, 2023
Heart-on-chip emerged as a potential tool for cardiac tissue engineering, recapitulating key physiological cues in cardiac pathophysiology. Controlled electrical stimulation and the ability to provide directly analyzed functional readouts are essential ...
Feng Zhang   +9 more
doaj   +1 more source

Drug Toxicity Evaluation Based on Organ-on-a-chip Technology: A Review

open access: yesMicromachines, 2020
Organ-on-a-chip academic research is in its blossom. Drug toxicity evaluation is a promising area in which organ-on-a-chip technology can apply. A unique advantage of organ-on-a-chip is the ability to integrate drug metabolism and drug toxic processes in
Ye Cong   +9 more
doaj   +1 more source

Clinical Significance of Clonal Hematopoiesis of Indeterminate Potential in Hematology and Cardiovascular Disease

open access: yesDiagnostics, 2022
Liquid profiling uses circulating tumor DNA (ctDNA) for minimal invasive tumor mutational profiling from peripheral blood. The presence of somatic mutations in peripheral blood cells without further evidence of a hematologic neoplasm defines clonal ...
Gregor Hoermann
doaj   +1 more source

Microfluidic heart on a chip for higher throughput pharmacological studies

open access: yes, 2015
We present the design of a higher throughput “heart on a chip” which utilizes a semi-automated fabrication technique to process sub millimeter sized thin film cantilevers of soft elastomers. Anisotropic cardiac microtissues which recapitulate the laminar
McCain, Megan Laura   +4 more
core   +1 more source

Low-cost on-chip clock jitter measurement scheme [PDF]

open access: yes, 2014
In this paper, we present a low-cost, on-chip clock jitter digital measurement scheme for high performance microprocessors. It enables in situ jitter measurement during the test or debug phase.
Giaffreda, Daniele   +25 more
core   +1 more source

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