Results 31 to 40 of about 132,211,819 (268)
Heart-on-a-Chip Model of Epicardial-Myocardial Interaction in Ischemia Reperfusion Injury. [PDF]
Adv Healthc MaterAbstractEpicardial cells (EPIs) form the outer layer of the heart and play an important role in development and disease. Current heart‐on‐a‐chip platforms still do not fully mimic the native cardiac environment due to the absence of relevant cell types, such as EPIs.
Bannerman D +15 more
europepmc +3 more sources
From cardiac tissue engineering to heart-on-a-chip: beating challenges [PDF]
Biomedical Materials, 2015 The heart is one of the most vital organs in the human body, which actively pumps the blood through the vascular network to supply nutrients to as well as to extract wastes from all other organs, maintaining the homeostasis of the biological system.
Zhang, Yu Shrike +7 more
openaire +4 more sources
, 2020 We demonstrated a bioelectronic heart-on-a-chip model for studying the effects of acute hypoxia on cardiac function. A microfluidic channel enabled rapid modulation of medium oxygenation, which mimicked the regimes induced by a temporary coronary ...
Breanna M. Duffy (8548554) +17 more
core +2 more sources
Conceptual Design of Micro-Bioreactors and Organ-on-Chips for Studies of Cell Cultures
Bioengineering, 2018 Engineering design of microbioreactors (MBRs) and organ-on-chip (OoC) devices can take advantage of established design science theory, in which systematic evaluation of functional concepts and user requirements are analyzed.
Carl-Fredrik Mandenius
doaj +1 more source
Fast electrically assisted regeneration of on-chip SERS substrates
, 2022 S.2923-2927A microfluidic chip approach utilising integrated electrically connected stationary SERS targets based on inkjet-printed silver nanoparticles is presented.
Belder, Detlev +7 more
core +1 more source
3D Inkjet-Bioprinted Lung-on-a-Chip
, 2023 There is an urgent need for physiologically relevant and customizable biochip models of human lung tissue to provide a niche for lung disease modeling and drug efficacy.
Dayoon Kang +11 more
core +1 more source
, 2020 We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing
Campos, C. D. M. +5 more
core +1 more source
Antisenescence Therapy Improves Function in a Human Model of Cardiac Fibrosis-on-a-Chip
, 2023 Cardiac fibrosis is a significant contributor to heart failure and is characterized by abnormal ECM deposition and impaired contractile function. We have previously developed a model of cardiac fibrosis via TGF-β treatment of engineered microtissues ...
Rupal Hatkar (582058) +12 more
core +1 more source
Haematologica, 2020 Intraluminal thrombus formation precipitates conditions such as acute myocardial infarction and disturbs local blood flow resulting in areas of rapidly changing blood flow velocities and steep gradients of blood shear rate.
Thomas Hoefer +9 more
doaj +1 more source
Bioprinting of Organ-on-Chip Systems: A Literature Review from a Manufacturing Perspective
Journal of Manufacturing and Materials Processing, 2021 This review discusses the reported studies investigating the use of bioprinting to develop functional organ-on-chip systems from a manufacturing perspective.
Ketan Thakare +5 more
doaj +1 more source