Results 71 to 80 of about 174,337 (252)

Sodium leak through K2P potassium channels and cardiac arrhythmia, an emerging theme. [PDF]

open access: yes, 2017
In this issue of EMBO Molecular Medicine, Decher et al (2017) identify a point mutation in the K2P2 (TREK‐1) potassium (K+) channel that changes function in just those ways expected to predispose to right ventricular outflow tract (RVOT) ventricular
Goldstein, Steve An
core   +2 more sources

Influence of cardiac tissue anisotropy on re-entrant activation in computational models of ventricular fibrillation

open access: yes, 2009
The aim of this study was to establish the role played by anisotropic diffusion in (i) the number of filaments and epicardial phase singularities that sustain ventricular fibrillation in the heart, (ii) the lifetimes of filaments and phase singularities,
Clayton, R.H.
core   +1 more source

Dynamics of conduction blocks in a model of paced cardiac tissue [PDF]

open access: yes, 2005
We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region.
C. H. Luo   +7 more
core   +1 more source

CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]

open access: yes, 2014
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core   +2 more sources

Electrocardiographic Abnormalities and Treatment with Benznidazole among Children with Chronic Infection by Trypanosoma cruzi: A Retrospective Cohort Study [PDF]

open access: yes, 2016
Background: Chronic infection by Trypanosoma cruzi could cause heart conduction disturbances. We sought to analyze electrocardiographic abnormalities among children with chronic T. cruzi infection with and without trypanocidal treatment with benznidazole.
Colantonio, Lisandro Damián   +3 more
core   +2 more sources

A study on stability analysis of atrial repolarization variability using ARX model in sinus rhythm and atrial tachycardia ECGs [PDF]

open access: yes, 2016
© 2016 Elsevier Ireland Ltd Background The interaction between the PTa and PP interval dynamics from the surface ECG is seldom explained. Mathematical modeling of these intervals is of interest in finding the relationship between the heart rate and ...
Langley, Philip   +5 more
core   +1 more source

Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system

open access: yesBiology Open, 2013
Summary During development, the ventricular conduction system (VCS) arises from the trabecular or spongy myocardium. VCS and trabecular myocytes proliferate at a significantly slower rate than compact zone myocardial cells, establishing a transmural cell
David S. Park   +6 more
doaj   +1 more source

Electrophysiological Mechanisms of Atrial Flutter [PDF]

open access: yes, 2006
Atrial flutter (AFL) is a common arrhythmia in clinical practice. Several experimental models such as tricuspid regurgitation model, tricuspid ring model, sterile pericarditis model and atrial crush injury model have provided important information about
Chen, Shin-Ann, Tai, Ching- Tai
core   +2 more sources

Home - About - Disclaimer - Privacy