Results 131 to 140 of about 163,785 (367)

Progression of coronary microvascular dysfunction to heart failure with preserved ejection fraction: a case report

open access: yesJournal of Medical Case Reports, 2019
Background In women with evidence of ischemia and no obstructive coronary artery disease the underlying mechanism is most often attributed to coronary microvascular dysfunction.
Sandy Joung   +8 more
doaj   +1 more source

Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure [PDF]

open access: yes, 2017
[Abstract] Epicardial adipose tissue has been proposed to participate in the pathogenesis of heart failure. The aim of our study was to assess the expression of thermogenic genes (Uncoupling protein 1 (UCP1), peroxisome proliferator-activated receptor ...
Carrasco-Chinchilla, Fernando   +11 more
core   +5 more sources

Sickle Cell Diastolic Cardiomyopathy and Mortality Risk: A Novel Echocardiographic Framework for Prognostic Stratification

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Cardiovascular complications are the leading cause of mortality in sickle cell anemia (SCA) patients. While extensive data have identified diastolic dysfunction (DD) to increase morbidity and mortality, the unique hemodynamic conditions inherent to SCA challenge the current recommendations to assess diastolic function. Thus, there is an urgent
Théo Simon   +20 more
wiley   +1 more source

Central and Obstructive Apneas in Heart Failure With Reduced, Mid-Range and Preserved Ejection Fraction

open access: yesFrontiers in Cardiovascular Medicine, 2019
Background: Although central apneas (CA) and obstructive apneas (OA) are highly prevalent in heart failure (HF), a comparison of apnea prevalence, predictors and clinical correlates in the whole HF spectrum, including HF with reduced ejection fraction ...
Chiara Borrelli   +17 more
doaj   +1 more source

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng   +4 more
wiley   +1 more source

НОВЫЕ АСПЕКТЫ ПАТОГЕНЕЗА И ДИАГНОСТИКИ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ С СОХРАНЁННОЙ ФРАКЦИЕЙ ВЫБРОСА В СОЧЕТАНИИ С САХАРНЫМ ДИАБЕТОМ 2 ТИПА

open access: yesАрхивъ внутренней медицины, 2014
In recent years, more attention is paid to chronic heart failure with preserved ejection fraction. This report examines not only the pathogenesis of diastolic heart failure, but the features of the pathogenesis of chronic heart failure with preserved ...
А. А. Снеткова   +2 more
doaj   +1 more source

Development of an efficient mice model of cancer‐associated cardiac cachexia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong   +9 more
wiley   +1 more source

Cardiorenal Syndrome Caused by Heart Failure with Preserved Ejection Fraction

open access: yesInternational Journal of Nephrology, 2011
Since cardiorenal dysfunction is usually secondary to multiple factors acting in concert (and not only reduced cardiac output) in the present paper we are going to focus on the interrelationship between heart failure with normal ejection fraction and the
Chiara Lazzeri   +3 more
doaj   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +15 more
wiley   +1 more source

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