Results 151 to 160 of about 211,923 (255)

Genotypic-specific heat shock response of vector susceptibility to Schistosoma mansoni. [PDF]

Ecosphere, 2022
Spaan JM, Leavitt N, Shen J, Bundy T, Burrows L, Ingram C, Maehara TR, Ndungu I, Mutuku M, Owino G, Odiere M, Steinauer ML.   +11 more
europepmc   +1 more source

A Pancreatitis‐Inspired Trypsinogen Nanoplatform Reprograms Tumor‐Associated Macrophages via NF‐κB for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
Trypsinogen‐loaded nanoparticles reprogram TAMs via NF‐κB/NLRP3, driving M2→M1 conversion and potent phagocytosis to unleash antitumor immunity. ABSTRACT Although reprogramming tumor‐associated macrophages (TAMs) represents a promising therapeutic strategy, approaches that are both precise and safe remain scarce.
Lei Cao, Yu He, Wenhao Li, Bo Gong, Han Lin, Jianlin Shi, Yuan Yong, Wencheng Wu   +7 more
wiley   +1 more source

Human milk-derived extracellular vesicles promote the heat shock response in polarized microglia. [PDF]

Cell Stress Chaperones
Storm JA, Lu J, Obtial MF, Wijenayake S.
europepmc   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

Response and adaptation of the transcriptional heat shock response to pressure. [PDF]

Front Microbiol
Coffin CH, Fisher LA, Crippen S, Demers P, Bartlett DH, Royer CA.   +5 more
europepmc   +1 more source

Inducible transcriptional condensates drive 3D genome reorganization in the heat shock response. [PDF]

Mol Cell, 2022
Chowdhary S, Kainth AS, Paracha S, Gross DS, Pincus D.   +4 more
europepmc   +1 more source

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

Advanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng, Lurong Li, Zhenghui Zhu, Chenyang Li, Huaiming Sang, Guoxin Zhang, Xuan Li, Yini Dang, Yuanyuan Li   +8 more
wiley   +1 more source

eIF3g binding to GUCG boxes located in mRNA coding regions enhances translation of mild heat shock response genes in the yeast Saccharomyces cerevisiae. [PDF]

Nucleic Acids Res
Kato H, Oguro A, Mao Y, Ochsner K, Casey H, Sakai G, Wan J, Usuki S, Tang L, Asano M, Bardiya N, Kaufman K, Ishiguro S, Tani N, Kumagai K, Nakamura A, Singh CR, Sakamoto T, Obayashi E, Qian SB, Asano K.   +20 more
europepmc   +1 more source

Two-step model of paleohexaploidy, ancestral genome reshuffling and plasticity of heat shock response in Asteraceae. [PDF]

Hortic Res, 2023
Kong X, Zhang Y, Wang Z, Bao S, Feng Y, Wang J, Yu Z, Long F, Xiao Z, Hao Y, Gao X, Li Y, Ding Y, Wang J, Lei T, Xu C, Wang J.   +16 more
europepmc   +1 more source

Origami Metamaterials Based on Low‐Melting‐Point Alloy Phase Transition: Breaking the Trade‐Off Between Reusability and Energy Absorption Quality

Advanced Science, EarlyView.
This work presents an origami metamaterial that integrates a low‐melting‐point alloy skeleton into an elastomeric shell. It dissipates energy through the metal's plastic deformation and recovers through the solid–liquid phase transition of the alloy together with the hyperelasticity of the shell.
Yupeng Liu, Wei Zhao, Chengjun Zeng, Jiuming Fan, Yanju Liu, Jinsong Leng   +5 more
wiley   +1 more source