Results 181 to 190 of about 321,164 (352)

Shock propagation in a complex laminate [PDF]

, 2014
The shock response of a complex laminate has been investigated using a single stage gas gun, with manganin pressure gauges employed to investigate the shock profile. The complex laminate investigated was known by the acronym TWCP and is a tape wrapped
Wood, David C.
core  

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

Advanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li, Tong Xiang, Yuanyuan Liu, Desheng Weng, Jingjing Zhao, Hao Chen, Yan Tang, Songzuo Xie, Hao Zhang, Jun Luo, Xinyi Yang, Qiuzhong Pan, Muping Di, Jianchuan Xia   +13 more
wiley   +1 more source

Abiotic Stresses Induce Heat Shock Factors to Regulate Small Heat Shock Protein Genes Expression in Arabidopsis thaliana

, 2007
熱逆境為植物的環境逆境之一，隨著溫室效應造成全球暖化日趨嚴重，也因此成為重要的關切議題。當植物暴露於熱逆境時，會產生共同的生理反應來抵抗高溫逆境，此反應稱為熱休克反應(heat shock response)，會大量合成一群新的蛋白質來保護細胞，這些蛋白質稱為熱休克蛋白(heat shock proteins, HSPs)，其中以低分子量熱休克蛋白(small HSPs, sHSPs)的種類與數量為最多，而sHSPs的合成被認為是經由熱休克轉錄因子(heat shock factors, HSFs ...
Huang, Tsung-Chih, 黃琮智
core  

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Mechanism of secondary renal injury in traumatic hemorrhagic shock model under a dry and heat desert environment

Scientific Reports
We established a swine model of traumatic hemorrhagic shock to assess secondary renal injury under dry-heat conditions to clarify the roles of cell pyroptosis and inflammatory response in traumatic hemorrhagic shock development.
Xinyue Yang, Jiajia Li, Feixing Liang, Jinquan Qu, Xiang Dong, Jiangwei Liu   +5 more
doaj   +1 more source

Genome-Wide Characterization of the Roles of Transcription Factors GAF and HSF in the Transcriptional Heat Shock Response

, 2017
Fabiana de Melo Duarte
openalex   +2 more sources

The heat shock response of Mycobacterium tuberculosis: linking gene expression, immunology and pathogenesis [PDF]

, 2002
Joseph A. Mangan, Richard Stabler, Philip D. Butcher, Butcher, PD, Wernisch, L, Lorenz Wernisch, Ken G. Laing, Graham R. Stewart, Young, DB, Stabler, R, Hinds, J, Mangan, JA, Jason Hinds, Wermisch, L, Stewart, GR, Laing, KG, Douglas B. Young   +16 more
core   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

(p)ppGpp - an important player during heat shock response. [PDF]

Microlife, 2023
Driller K, Cornejo FA, Turgay K.
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source