Results 141 to 150 of about 202,314 (262)

Short heat shock factor A2 regulates heat resistance and growth balance in <i>Arabidopsis</i>. [PDF]

Elife
Chen W, Zhao J, Tao Z, Zhang S, Bei X, Lu W, Qi X.   +6 more
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Multifaceted roles of mammalian heat shock factor 1 in the central nervous system. [PDF]

Cell Stress Chaperones
Rozema NB, Gomez-Pastor R.
europepmc   +1 more source

The class B heat shock factor HSFB1 regulates heat tolerance in grapevine. [PDF]

Hortic Res, 2023
Chen H, Liu X, Li S, Yuan L, Mu H, Wang Y, Li Y, Duan W, Fan P, Liang Z, Wang L.   +10 more
europepmc   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

CIRCADIAN CLOCK-ASSOCIATED 1 represses thermotolerance by inhibiting <i>HEAT SHOCK FACTOR A2</i> expression in nonheading Chinese cabbage. [PDF]

Hortic Res
He Y, Xiao D, Hou X, Li Y, Zhu H.
europepmc   +1 more source

Conserved and variable heat stress responses of the Heat Shock Factor transcription factor family in maize and Setaria viridis. [PDF]

Plant Direct, 2023
Myers ZA, Wootan CM, Liang Z, Zhou P, Engelhorn J, Hartwig T, Nathan SM.   +6 more
europepmc   +1 more source

Mixed‐Polymer Hole Transport Layers Reinforce Au‐Anode Top Emitting Perovskite Light Emitting Diodes

Advanced Science, EarlyView.
Au‐anode corrosion is shown to occur rapidly under voltage bias in MAPbI3 perovskite LEDs. Resulting Au+ migration quickly leads to device shorting and unstable emission during constant current driving. We demonstrate that using a simple mixed‐polymer hole transport layer containing polyTPD and PVK can reduce Au‐corrosion and stabilize LED operation ...
James C. Loy, Jisu Hong, Tuo Hu, Xu He, Antoine Kahn, Barry P. Rand   +5 more
wiley   +1 more source

Characterization of the heat shock factor RcHsfA6 in Rosa chinensis and function in the thermotolerance of Arabidopsis. [PDF]

BMC Plant Biol
Kang Y, Yang Y, Sun P, Li M, Wang H, Sun X, Jin W.   +6 more
europepmc   +1 more source

Loss of heat shock factor initiates intracellular lipid surveillance by actin destabilization. [PDF]

Cell Rep, 2022
Watterson A, Arneaud SLB, Wajahat N, Wall JM, Tatge L, Beheshti ST, Mihelakis M, Cheatwood NY, McClendon J, Ghorashi A, Dehghan I, Corley CD, McDonald JG, Douglas PM.   +13 more
europepmc   +1 more source