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The Role of Heat Shock Factors in Mammalian Spermatogenesis
2017Heat shock transcription factors (HSFs), as regulators of heat shock proteins (HSPs) expression, are well known for their cytoprotective functions during cellular stress. They also play important yet less recognized roles in gametogenesis. All HSF family members are expressed during mammalian spermatogenesis, mainly in spermatocytes and round ...
Wieslawa, Widlak, Natalia, Vydra
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Activation of heat-shock transcription factor in rat heart after heat shock and exercise
American Journal of Physiology-Cell Physiology, 1995Stress-induced transcriptional regulation of the heat-shock proteins (HSP) is mediated by activation and binding of the heat-shock transcription factors (HSF) to the heat-shock element (HSE). Given the similarities between the stressors known to activate the HSF in cultured cells and the physiological stresses known to occur during exercise, HSF ...
M, Locke +5 more
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Heat shock factors and the control of the stress response
Biochemical Pharmacology, 2000Living cells are continually challenged by conditions which cause acute and chronic stress. To adapt to environmental changes and survive different types of injuries, eukaryotic cells have evolved networks of different responses which detect and control diverse forms of stress.
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Journal of Urology, 2010
Varicocele may be associated with normozoospermia or oligozoospermia. Much controversy still exists regarding the diagnosis, management and pathophysiology of spermatogenesis alterations associated with varicocele. The increased temperature induced by varicocele and stress in general may activate heat shock proteins and heat shock factors with a ...
FERLIN, ALBERTO +6 more
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Varicocele may be associated with normozoospermia or oligozoospermia. Much controversy still exists regarding the diagnosis, management and pathophysiology of spermatogenesis alterations associated with varicocele. The increased temperature induced by varicocele and stress in general may activate heat shock proteins and heat shock factors with a ...
FERLIN, ALBERTO +6 more
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Growth Factors, Heat-Shock Proteins and Regeneration in Echinoderms
Journal of Experimental Biology, 2001ABSTRACT The study of regeneration in armed echinoderm species, including crinoids, ophiuroids and asteroids, is attracting increasing attention. Recent interest has focused on the presence and potential role of growth factors, including members of the nerve growth factor (NGF) and transforming growth factor-beta (TGF-β) families, in the
M. Patruno +4 more
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In vitro activation of purified human heat shock factor by heat
Biochemistry, 1995A major regulatory step in the heat-induced transcription of heat shock protein (hsp) genes in eukaryotes is the activation of heat shock factor (HSF). In metazoans and Schizosaccharomyces pombe, HSF is present in unstressed cells but is unable to bind to its target DNA sequence element, the heat shock element (HSE).
J S, Larson, T J, Schuetz, R E, Kingston
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1996
The inducible regulation of heat shock gene transcription is mediated by a family of heat shock factors (HSF) that respond to diverse forms of physiological and environmental stress including elevated temperature, amino acid analogs, heavy metals, oxidative stress, anti-inflammatory drugs, arachidonic acid, and a number of pathophysiological disease ...
R I, Morimoto, P E, Kroeger, J J, Cotto
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The inducible regulation of heat shock gene transcription is mediated by a family of heat shock factors (HSF) that respond to diverse forms of physiological and environmental stress including elevated temperature, amino acid analogs, heavy metals, oxidative stress, anti-inflammatory drugs, arachidonic acid, and a number of pathophysiological disease ...
R I, Morimoto, P E, Kroeger, J J, Cotto
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Regulation of the heat shock response by heat shock transcription factors
2006Ville Hietakangas, Lea Sistonen
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