Results 131 to 140 of about 650,866 (279)

Heat Shock Factor 1 Inhibition: A Novel Anti-Cancer Strategy with Promise for Precision Oncology. [PDF]

Cancers (Basel), 2023
Gumilar KE, Chin Y, Ibrahim IH, Tjokroprawiro BA, Yang JY, Zhou M, Gassman NR, Tan M.   +7 more
europepmc   +1 more source

MAGTWIST: A Magnetically‐Driven Rotary Actuator Using a Traveling‐Wave With Integrated Stiffness Tunability

Advanced Functional Materials, EarlyView.
MAGTWIST: A compact magnetic rotary actuator, enabling smooth, stepless rotation, and on‐demand locking. Inspired by peristalsis, a soft polymer belt generates a traveling‐wave, enabling 270° rotation when heated. Cooling stiffens the belt, locking it in position and enabling it to withstand high loads.
Simon Frieler, Jean‐Paul P.M. de Vries, Sarthak Misra, Venkatasubramanian Kalpathy Venkiteswaran   +3 more
wiley   +1 more source

The Skn7 Response Regulator of \u3ci\u3eSaccharomyces cerevisiae\u3c/i\u3e Interacts with Hsf1 In Vivo and Is Required for the Induction of Heat Shock Genes by Oxidative Stress [PDF]

, 2000
The Skn7 response regulator has previously been shown to play a role in the induction of stress-responsive genes in yeast, e.g., in the induction of the thioredoxin gene in response to hydrogen peroxide.
Erkine, Alexander M., Gross, David S., Johnson, Anthony L., Johnston, Leland H., Makino, Kozo, Morgan, Brian, Raitt, Desmond C.   +6 more
core   +1 more source

Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress

, 2005
BackgroundHeat shock factor (HSF/HSF1) not only is the transcription factor primarily responsible for the transcriptional response of cells to physical and chemical stress but also coregulates other important signaling pathways.
T. Guettouche, Frank Boellmann, William Arbuthnot Sir Lane, R. Voellmy   +3 more
semanticscholar   +1 more source

Bioinspired Stabilization of Fluorescent Au@SiO2 Tracers for Multimodal Biological Imaging

Advanced Functional Materials, EarlyView.
This study demonstrates a bioinspired stabilization strategy for fluorescent gold‐silica nanoparticles. Inspired by natural biosilica maturation, high‐temperature calcination transforms the silica shells, preventing dissolution in cell culture media and intracellular environments.
Wang Sik Lee, Henry Lee, Patricia Taladriz‐Blanco, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Alke Petri‐Fink   +5 more
wiley   +1 more source

Predicting Genetic Regulatory Response Using Classification

, 2004
We present a novel classification-based method for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple organisms such as Saccharomyces cerevisiae, we can learn a decision rule for predicting whether a ...
Freund, Yoav, Kundaje, Anshul, Leslie, Christina, Middendorf, Manuel, Wiggins, Chris   +4 more
core   +4 more sources

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Developmental regulation of the heat shock response by nuclear transport factor karyopherin-α3 [PDF]

, 2001
During early stages of Drosophila development the heat-shock response cannot be induced. It is reasoned that the adverse effects on cell cycle and cell growth brought about by Hsp70 induction must outweigh the beneficial aspects of Hsp70 induction in the
Chen, Tianxin, Fang, Xiang-dong, Parker, Carl S., Tran, Kim   +3 more
core  

Gravitational Quenching in Massive Galaxies and Clusters by Clumpy Accretion

, 2007
We consider a simple gravitational-heating mechanism for the long-term quenching of cooling flows and star formation in massive dark-matter haloes hosting ellipticals and clusters.
Agertz, Avishai Dekel, Babul, Barkana, Best, Binney, Birnboim, Birnboim, Blitz, Blumenthal, Bonnor, Borgani, Bower, Bryan, Brüggen, Bullock, Cattaneo, Cen, Chandran, Chen, Chen, Ciotti, Cox, Croton, Dekel, Dekel, Dekel, Dekel, Donahue, Ebert, El-Zant, Fabian, Faltenbacher, Fardal, Fukazawa, Ghigna, Gnat, Gnedin, Helsdon, Hopkins, Humphrey, Katz, Katz, Kaufmann, Kay, Kereš, Kim, Klein, Kolmogorov, Krause, Landau, Lauer, Lin, Loeb, Maller, Maloney, Mathews, McCarthy, Mo, Mo, Motl, Murray, Murray, Naab, Nagai, Neistein, Neistein, Noeske, Oort, Osmond, Ostriker, Popo, Pratt, Rees, Sage, Sarzi, Sijacki, Silk, Spitzer, Sternberg, Sutherland, Voit, Wechsler, White, Wise, Yuval Birnboim, Zakamska   +86 more
core   +1 more source

Frontier Advances of Emerging High‐Entropy Anodes in Alkali Metal‐Ion Batteries

Advanced Functional Materials, EarlyView.
Recent advances in microscopic morphology control of high‐entropy anode materials for alkali metal‐ion batteries. Abstract With the growing demand for sustainable energy, portable energy storage systems have become increasingly critical. Among them, the development of rechargeable batteries is primarily driven by breakthroughs in electrode materials ...
Liang Du, Kaidi Zhang, Liang Wang, Di Zhao, Mengqing Hu, Mingli Li, Ming Zhou, Zhenzhen Wu, Mengyang Dong, Bo Fu, Porun Liu, Yun Wang, Hongxia Wang, Yuantong Gu, Lei Zhang   +14 more
wiley   +1 more source