Results 141 to 150 of about 198,852 (250)

A Worm‐Inspired Origami Robot with Multimodal Locomotion for Adaptive Mobility in Complex Pipeline Environments

Advanced Science, EarlyView.
An origami worm‐inspired robot achieves multimodal locomotion in confined pipelines through mechatronic integration that embeds actuation, control, and communication within each origami module. Large, reversible configuration and dimensional changes enable 25 gaits synthesized by a unified framework across peristaltic, inchworm, and wheel‐rolling modes
Qiwei Zhang, Kangning Tan, Zihan He, Hongsen Pang, Yanjie Wang, Hongbin Fang, Jian Xu   +6 more
wiley   +1 more source

A Polymorphism in the Gene Encoding Heat Shock Factor 1 (<i>HSF1</i>) Increases the Risk of Type 2 Diabetes: A Pilot Study Supports a Role for Impaired Protein Folding in Disease Pathogenesis. [PDF]

Life (Basel), 2022
Klyosova E, Azarova I, Polonikov A.
europepmc   +1 more source

Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy

Advanced Science, EarlyView.
A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li, Ruixiao Hu, Jie Mao, Jin Wo, Yunsong Zhang, Liang Chen, Ying Liu, Zhibo Li, Yongxin Lin, Minghui Du, Yaofei Chen, Libing Zhou, Tuan Guo   +12 more
wiley   +1 more source

Multifaceted roles of mammalian heat shock factor 1 in the central nervous system. [PDF]

Cell Stress Chaperones
Rozema NB, Gomez-Pastor R.
europepmc   +1 more source

Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells. [PDF]

Elife, 2021
Vydra N, Janus P, Kus P, Stokowy T, Mrowiec K, Toma-Jonik A, Krzywon A, Cortez AJ, Wojtas B, Gielniewski B, Jaksik R, Kimmel M, Widlak W.   +12 more
europepmc   +1 more source

Understanding the Catalytic Determinant role of Diaphorase‐Like Subunit in Formate Dehydrogenases via Redox Couples

Advanced Science, EarlyView.
A unique mechanism of catalytic bias regulated by diaphorase‐like subunit in formate dehydrogenase from Rhodobacter aestuarii is revealed. The diaphorase‐like subunit functions act as a biological “voltage rheostat” that controls the slow release of NADH to regulate redox balance, biasing the enzyme's catalytic preference toward CO2 reduction over ...
Kuncheng Zhang, Weisong Liu, Hao Su, Huijuan Cui, Yuanming Wang, Zhiguang Zhu, Chun You, Lingling Zhang   +7 more
wiley   +1 more source

<i>ACTA2</i> Pathogenic Variants Activating Heat Shock Factor 1 and Increasing Cholesterol Biosynthesis in Smooth Muscle Cells Predispose to Early Onset Atherosclerosis. [PDF]

Circ Genom Precis Med
Boerio ML, Chattopadhyay A, Duan XY, Karla A, Calderon Martinez E, Pinard A, Morse AK, Reddy D, Dharma S, Velasco-Torrez W, Marcadier J, Prakash SK, Shalhub S, De Backer J, Jeremy R, Morris SA, Yetman AT, Braverman AC, Milewicz DM.   +18 more
europepmc   +1 more source

Transcriptional regulation of small heat shock protein genes by heat shock factor 1 (HSF1) in Liriomyza trifolii under heat stress. [PDF]

Cell Stress Chaperones, 2021
Chang YW, Wang YC, Zhang XX, Iqbal J, Lu MX, Du YZ.   +5 more
europepmc   +1 more source

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness. [PDF]

Front Mol Biosci
Xu C, Zhou Q, Meng X, Zhou J, Yu X, Zheng J, Yi H, Huang G, Xu W.   +8 more
europepmc   +1 more source