Results 111 to 120 of about 198,478 (151)

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer. [PDF]

Nat Commun, 2020
Levi-Galibov O, Lavon H, Wassermann-Dozorets R, Pevsner-Fischer M, Mayer S, Wershof E, Stein Y, Brown LE, Zhang W, Friedman G, Nevo R, Golani O, Katz LH, Yaeger R, Laish I, Porco JA, Sahai E, Shouval DS, Kelsen D, Scherz-Shouval R.   +19 more
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HSF1Base: A Comprehensive Database of HSF1 (Heat Shock Factor 1) Target Genes. [PDF]

Int J Mol Sci, 2019
Kovács D, Sigmond T, Hotzi B, Bohár B, Fazekas D, Deák V, Vellai T, Barna J.   +7 more
europepmc   +1 more source

Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase. [PDF]

Mol Cell, 2019
Su KH, Dai S, Tang Z, Xu M, Dai C.
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Heat Shock Factor 1 Predicts Poor Prognosis of Gastric Cancer. [PDF]

Yonsei Med J, 2018
Kim SJ, Lee SC, Kang HG, Gim J, Lee KH, Lee SH, Chun KH.   +6 more
europepmc   +1 more source

Excitatory synapse impairment and mitochondrial dysfunction in Huntington's disease: heat shock factor 1 (HSF1) converging mechanisms.

Neural Regen Res, 2020
Zarate N, Gomez-Pastor R.
europepmc   +1 more source

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Molecular mechanisms of heat shock factor 1 regulation

Trends in Biochemical Sciences, 2022
To thrive and to fulfill their functions, cells need to maintain proteome homeostasis even in the face of adverse environmental conditions or radical restructuring of the proteome during differentiation. At the center of the regulation of proteome homeostasis is an ancient transcriptional mechanism, the so-called heat shock response (HSR), orchestrated
Szymon W. Kmiecik, Matthias P. Mayer
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Roles of heat shock factor 1 beyond the heat shock response

Cellular and Molecular Life Sciences, 2018
Various stress factors leading to protein damage induce the activation of an evolutionarily conserved cell protective mechanism, the heat shock response (HSR), to maintain protein homeostasis in virtually all eukaryotic cells. Heat shock factor 1 (HSF1) plays a central role in the HSR. HSF1 was initially known as a transcription factor that upregulates
Barna János, Csermely Péter, Vellai Tibor   +2 more
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Chilo suppressalis heat shock proteins are regulated by heat shock factor 1 during heat stress

Insect Molecular Biology, 2022
Abstract Heat shock factor 1 (HSF1) functions to maintain cellular and organismal homeostasis by regulating the expression of target genes, including those encoding heat shock proteins (HSPs). In the present study, the gene encoding HSF1 was cloned from the rice pest Chilo suppressalis
Chuan‐Lei Dong, Zhu Feng, Ming‐Xing Lu, Yu‐Zhou Du   +3 more
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Heat Shock Inhibits Activation of NF-κB in the Absence of Heat Shock Factor-1

Biochemical and Biophysical Research Communications, 2002
The heat shock response is known to inhibit NF-kappaB activation and NF-kappaB-dependent gene expression. Herein we determined if cells lacking heat shock factor-1 (HSF-1), the major transcription factor regulating heat shock protein gene expression, have an altered ability to modulate NF-kappaB activation.
Vivek, Malhotra, Tonyia, Eaves-Pyles, Kelli, Odoms, Gina, Quaid, Thomas P, Shanley, Hector R, Wong   +5 more
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Role of Heat Shock Transcriptional Factor 1 and Heat Shock Proteins in Cardiac Hypertrophy

Trends in Cardiovascular Medicine, 2008
Cardiac hypertrophy is an independent risk factor for cardiovascular disease. Initially, cardiac hypertrophy is an adaptive response to increased wall stress, but sustained stress leads to heart failure. It remains unclear how the transition from adaptive cardiac hypertrophy to maladaptive cardiac hypertrophy occurs.
Haruhiro, Toko, Tohru, Minamino, Issei, Komuro   +2 more
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