Results 91 to 100 of about 543,466 (295)

Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1 [PDF]

, 2018
Cruciferous vegetables are rich sources of glucosinolates which are the biogenic precursor molecules of isothiocyanates (ITCs). The relationship between the consumption of cruciferous vegetables and chemoprotection has been widely documented in ...
Ahn, Ali, Andreasson, Baird, Barillari, Bast, Bommareddy, Boyanapalli, Bravi, Brown, Calderwood, Cang, Castellani, Ceriello, Chen, Chen, Chen, Cheung, Chorley, Chou, Chowdhry, Costa, Cuddihy, Dai, Daxenbichler, Dayalan Naidu, Dayalan Naidu, Dayalan Naidu, Dinkova-Kostova, Engerud, Fahey, Fofaria, Fukagawa, Gan, Gao, Gerhauser, Getahun, Gupta, Gupta, Hahm, Hasegawa, Hayes, Hector, Hong, Hu, Hu, Huong, Hwang, Itoh, Jakubikova, Jeong, Joseph, Jutooru, Kensler, Khamis, Kolm, Kong, Kong, Kong, Lai, Lawson, Lee, Li, Liu, Liu, Liu, Lo, Ma, Mahalingaiah, Marcotte, McMahon, McMahon, Meakin, Mehlman, Mi, Mi, Mi, Mi, Mithen, Moon, Muntane, Nagami, Neef, Neo, Ohnishi, Okubo, Olagnier, Pajares, Palaniswamy, Pawlik, Praprotnik, Ramirez, Rose, Rose, Saito, Santagata, Sayeed, Schulz, Sharma, Shroff, Sies, Singh, Singh, Suzuki, Tang, Trachootham, Tyndall, Visanji, Wang, Wang, Wang, Wang, Wang, Wang, Wu, Wu, Xiao, Xiao, Xiao, Xiao, Xiao, Xiao, Xiao, Xiao, Xu, Yates, Yeh, Yin, Yoda, Yu, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zuehlke   +137 more
core   +2 more sources

Interaction between Molten Al‐Killed Mn–B Steel and Carbon‐Bonded MgO Refractories Based on Recyclates

Advanced Engineering Materials, EarlyView.
High‐temperature interactions between low‐sulfur Al‐killed Mn–B steel and MgO–C refractories (0 and 50 wt% recyclates) are studied via finger immersion tests (1600 °C). Surface‐active elements influence infiltration. MgO/CaS layer forms, along with spinel and calcium silicate.
Matheus Roberto Bellé, Lukas Neubert, Anton Yehorov, Till M. J. Stadtmüller, Christos G. Aneziris, Olena Volkova   +5 more
wiley   +1 more source

Heat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-derived activator of caspase to promote pancreatic tumorigenesis

Journal of Experimental & Clinical Cancer Research, 2017
Background As a relatively conservative transcriptional regulator in biological evolution, heat shock factor 1 (HSF1) is activated by, and regulates the expression of heat shock proteins (HSPs) in response to a variety of stress conditions.
Wenjin Liang, Yong Liao, Jing Zhang, Qi Huang, Wei Luo, Jidong Yu, Jianhua Gong, Yi Zhou, Xuan Li, Bo Tang, Songqing He, Jinghong Yang   +11 more
doaj   +1 more source

New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumour cell survival. [PDF]

, 2017
© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which
Kirton, Stewart
core   +2 more sources

Induction of the Heat Shock Pathway during Hypoxia Requires Regulation of Heat Shock Factor by Hypoxia-inducible Factor-1 [PDF]

Journal of Biological Chemistry, 2006
Activation of heat shock proteins (Hsps) is critical to adaptation to low oxygen levels (hypoxia) and for enduring the oxidative stress of reoxygenation. Hsps are known to be regulated by heat shock factor (Hsf), but our results demonstrate an unexpected regulatory link between the oxygen-sensing and heat shock pathways.
Nathan A, Baird, Douglas W, Turnbull, Eric A, Johnson   +2 more
openaire   +2 more sources

Influence of Sample Preparation and Processing Procedures on the Thermal Diffusivity of MgO‐C Refractories

Advanced Engineering Materials, EarlyView.
The thermal diffusivity of MgO‐C refractories is highly sensitive to sample preparation and processing procedures. In this article, the effects of coking sequence, machining conditions, structural inhomogeneity, and graphite coating application on measurements using laser flash apparatus are systematically investigated.
Luyao Pan, Rhena Wulf, Till M. J. Stadtmüller, Christos G. Aneziris, Tobias M. Fieback   +4 more
wiley   +1 more source

Heat shock induces rapid resorption of primary cilia [PDF]

, 2012
Primary cilia are involved in important developmental and disease pathways, such as the regulation of neurogenesis and tumorigenesis. They function as sensory antennae and are essential in the regulation of key extracellular signalling systems.
Anckar, Baker, Berbari, Boyault, Breunig, Caspary, Corbit, Cotto, Davenport, Fliegauf, Gherman, Han, Haycraft, Kültz, Lange, McGlashan, Meimaridou, Nauli, Ng, Nigg, Overgaard, Pedersen, Pugacheva, Quarmby, Rohatgi, Rosenbaum, Schneider, Seeley, Singla, Taipale, Takaki, Weis, Williams   +32 more
core   +1 more source

Temporal requirements of heat shock factor‐1 for longevity assurance [PDF]

Aging Cell, 2012
SummaryReducing the activity of the insulin/IGF‐1 signaling pathway (IIS) modifies development, elevates stress resistance, protects from toxic protein aggregation (proteotoxicity), and extends lifespan (LS) of worms, flies, and mice. In the nematode Caenorhabditis elegans, LS extension by IIS reduction is entirely dependent upon the activity of the ...
Yuli, Volovik, Moria, Maman, Tatyana, Dubnikov, Michal, Bejerano-Sagie, Derek, Joyce, Erik A, Kapernick, Ehud, Cohen, Andrew, Dillin   +7 more
openaire   +2 more sources

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

The dynamics and high-energy emission of conductive gas clouds in supernova-driven galactic superwinds

, 2005
In this paper we present high-resolution hydrodynamical models of warm ionized clouds embedded in a superwind, and compare the OVI and soft X-ray properties to the existing observational data.
A. D'Ercole, A. Marcolini, Adelberger, Aloisi, Anders, Asai, Axon, Bedogni, Begelman, Bicknell, Bland, Bland-Hawthorn, C. G. Hoopes, Cardelli, Castor, Cecil, Cecil, Chandran, Chevalier, Cowie, Cowie, D'Ercole, D. K. Strickland, Dahlem, Dahlem, Dahlem, Devine, Edgar, Ettori, Fabbiano, Ferrara, Fragile, Frye, González Delgado, Gorti, Heckman, Heckman, Heckman, Heckman, Heckman, Heckman, Heckman, Heckman, Hoopes, Hoopes, Indebetouw, Kaastra, Klein, Kunth, Lamb, Landau, Lehnert, Lehnert, Lehnert, Leitherer, Liedahl, Mac Low, Martin, Mathews, McCarthy, McKee, McKee, Mellema, Mewe, Mewe, Morrison, Narayan, Norman, Ohyama, Origlia, Ostriker, Otte, Pettini, Pettini, Phillips, Raymond, Read, Ritchmyer, Scannapieco, Schurch, Shchekinov, Shu, Strickland, Strickland, Strickland, Strickland, Strickland, Strickland, Strickland, Suchkov, Suchkov, Sutherland, T. M. Heckman, Vieser, Vikhlinin, Wang, Watson, Weaver, Weaver, Woodward, Xia   +100 more
core   +1 more source