Results 171 to 180 of about 5,347,852 (306)

Cytosolic heat shock protein 90 is required for photoreceptor outer segment development and vision. [PDF]

J Biol Chem
Aliff HL, Crockett AB, Munezero D, Reid C, Bockius HG, Kuzak SG, Rhodes S, Saravanan T, Ramamurthy V.   +8 more
europepmc   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

Advanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen, Ming Li, Xuesheng Wang, Jiajia Sun, Ziyuan Zhang, Yongfeng Gong, Benkang Shi, Nengwang Yu, Yunuo Mao, Shengtian Zhao, Xiulin Zhang, Liqiang Guo   +11 more
wiley   +1 more source

Revisiting the Small Heat Shock Protein Family in <i>Caenorhabditis elegans:</i> Insights from Phylogenetic, Structural, and Functional Analyses. [PDF]

MicroPubl Biol
Kamath R, Kasturi P.
europepmc   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies. [PDF]

Adv Sci (Weinh)
Zhang B, Zou X, Zhou J, Sun Q, Chen D.
europepmc   +1 more source

Micro/Nanoscale Acoustic Manipulation: From Particle Control to Autonomous Microswimmers

Advanced Science, EarlyView.
This conceptual framework illustrates acoustic technology as a multifunctional platform enabling passive particle manipulation across scales and autonomous propulsion of microswimmers. ABSTRACT Acoustic manipulation and propulsion technologies have emerged as powerful platforms for micro/nanoscale control, enabled by their non‐contact operation, label ...
Jiahui Chu, Lemin Zhang, Xu Wang, Wenzong Li, Yahua Liu   +4 more
wiley   +1 more source

Development of domain-specific probes of <i>Plasmodium falciparum</i> heat shock protein 70-1. [PDF]

Antimicrob Agents Chemother
Keeler AM, Ibrasheva G, Boger EG, Chen Y, Petruzziello PE, Schroeder EA, Mansfield CR, Sylvester K, Fleming CD, Hughes PF, Haystead TAJ, Fitzgerald MC, Derbyshire ER.   +12 more
europepmc   +1 more source

HEAT-SHOCK PROTEINS AND ARTHRITIS [PDF]

Rheumatology, 1989
openaire   +2 more sources

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source

Fluorescence Immunosensor with Phage Antibodies for Heat Shock Protein 70 Detection. [PDF]

Biosensors (Basel)
Guliy OI, Eremin SA, Mukhametova LI, Kozlov ES, Grinev VS, Staroverov SA, Karavaeva OA, Fursova KK, Brovko FA, Dykman LA, Liu Q.   +10 more
europepmc   +1 more source