Results 31 to 40 of about 474,171 (296)
Frontiers in Plant Science, 2022 The expression of heat shock proteins is considered a central adaptive mechanism to heat stress. This study investigated the expression of heat shock proteins (HSPs) and other stress-protective proteins against heat stress in cowpea genotypes under field
Tonny I. Selinga +10 more
doaj +1 more source
YoeB toxin is activated during thermal stress. [PDF]
, 2015 Type II toxin-antitoxin (TA) modules are thought to mediate stress-responses by temporarily suppressing protein synthesis while cells redirect transcription to adapt to environmental change.
Garza-Sánchez, Fernando +2 more
core +1 more source
Proteotoxic stress reprograms the chromatin landscape of SUMO modification [PDF]
, 2015 The small ubiquitin-like modifier 2 (SUMO-2) is required for survival when cells are exposed to treatments that induce proteotoxic stress by causing the accumulation of misfolded proteins.
Anne Seifert +4 more
core +3 more sources
Journal of Radiation Research and Applied Sciences, 2015 The radioprotective effect of acetyl salicylic acid against radiation injury to rat salivary glands was reported but its interrelationship with the expression of heat shock protein 60; an endogenous cytoprotectant against various stressful stimuli has ...
D.G. Mohamed, R.M. Amin
doaj +1 more source
Absence of ataxin-3 leads to enhanced stress response in C. elegans. [PDF]
PLoS ONE, 2011 Ataxin-3, the protein involved in Machado-Joseph disease, is able to bind ubiquitylated substrates and act as a deubiquitylating enzyme in vitro, and it has been involved in the modulation of protein degradation by the ubiquitin-proteasome pathway.
Ana João Rodrigues +6 more
doaj +1 more source
Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress [PDF]
, 2014 The heat-shock response is a complex cellular program that induces major changes in protein translation, folding and degradation to alleviate toxicity caused by protein misfolding.
Chan, Gerard T. +8 more
core +2 more sources
Journal of Inflammation, 2005 Background Viruses remain one of the inducers of the stress response in the infected cells. Heat shock response induced by vaccinia virus (VV) infection was studied in vitro in human blood monocyte derived macrophages (MDMs) as blood cells usually ...
Dziedzic Jakub +4 more
doaj +1 more source
Candidate stress biomarkers for queen failure diagnostics
BMC Genomics, 2020 Background Queen failure is a persistent problem in beekeeping operations, but in the absence of overt symptoms it is often difficult, if not impossible, to ascertain the root cause. Stressors like heat-shock, cold-shock, and sublethal pesticide exposure
Alison McAfee +5 more
doaj +1 more source
Aneuploidy and proteotoxic stress in cancer [PDF]
, 2015 Although nearly ubiquitous in cancer, aneuploidy exerts detrimental effects on human cells. We recently demonstrated that aneuploid human cells exhibit impaired heat shock factor protein 1 (HSF1) and HSP90 function, suggesting a functional link between ...
Donnelly, N., Storchova, Z.
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The heat shock response in neurons and astroglia and its role in neurodegenerative diseases
Molecular Neurodegeneration, 2017 Protein inclusions are a predominant molecular pathology found in numerous neurodegenerative diseases, including amyotrophic lateral sclerosis and Huntington’s disease.
Rebecca San Gil +3 more
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