Results 31 to 40 of about 465,173 (296)

Hsp70 in mitochondrial biogenesis [PDF]

, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
A. Tzagoloff, A. Tzagoloff, A.J. Caplan, A.J. Caplan, B.D. Gambill, B.S. Glick, C.K. Suzuki, D. Ang, D. M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.P. Atencio, E. Ikeda, E. Kutejová, E.A. Craig, E.A. Craig, F.-U. Hartl, G.S.P. Groot, H.R.B. Pelham, J. Ostermann, J. Rassow, J.F. Dice, J.P. Hendrick, K. Liberek, L. Dyck van, M. Eilers, M. Kiebler, M. Schleyer, M.-J. Gething, M.Y. Cheng, N. Rowley, N. Wang, P. Borst, P. Terpstra, P.-J. Kang, R. A. Stuart, R.A. Stuart, R.A. Stuart, R.B. Deshaies, R.G. Hadikusumo, R.J. Nelson, R.P. Beckman, S. Lindquist, S. Rospert, S.T. Hwang, T. Langer, U.C. Manning-Krieg, W. Neupert, W. Neupert, W. Voos, W.J. Chirico, Z. Xia   +53 more
core   +1 more source

Transcriptional and translational dynamics underlying heat shock response in the thermophilic crenarchaeon Sulfolobus acidocaldarius

mBio, 2023
High-temperature stress is critical for all organisms and induces a profound cellular response. For Crenarchaeota, little information is available on how heat shock affects cellular processes and on how this response is regulated.
Rani Baes, Felix Grünberger, Sébastien Pyr dit Ruys, Mohea Couturier, Sarah De Keulenaer, Sonja Skevin, Filip Van Nieuwerburgh, Didier Vertommen, Dina Grohmann, Sébastien Ferreira-Cerca, Eveline Peeters   +10 more
doaj   +1 more source

YoeB toxin is activated during thermal stress. [PDF]

, 2015
Type II toxin-antitoxin (TA) modules are thought to mediate stress-responses by temporarily suppressing protein synthesis while cells redirect transcription to adapt to environmental change.
Garza-Sánchez, Fernando, Hayes, Christopher S, Janssen, Brian D   +2 more
core   +1 more source

Hopf bifurcation in a gene regulatory network model: Molecular movement causes oscillations [PDF]

, 2015
Gene regulatory networks, i.e. DNA segments in a cell which interact with each other indirectly through their RNA and protein products, lie at the heart of many important intracellular signal transduction processes.
Chaplain, M, Ptashnyk, M, Sturrock, M
core   +1 more source

Involvement of heat shock proteins 60 in acetyl salicylic acid radioprotection of Albino rat submandibular salivary gland

Journal of Radiation Research and Applied Sciences, 2015
The radioprotective effect of acetyl salicylic acid against radiation injury to rat salivary glands was reported but its interrelationship with the expression of heat shock protein 60; an endogenous cytoprotectant against various stressful stimuli has ...
D.G. Mohamed, R.M. Amin
doaj   +1 more source

Rsp5/​Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress [PDF]

, 2014
The heat-shock response is a complex cellular program that induces major changes in protein translation, folding and degradation to alleviate toxicity caused by protein misfolding.
Chan, Gerard T., Comyn, Sophie A., Deshaies, Raymond J., Fang, Nancy N., Gsponer, Joerg, Mayor, Thibault, Persaud, Avinash, Rotin, Daniela, Zhu, Mang   +8 more
core   +2 more sources

Heat shock protein and heat shock factor 1 expression and localization in vaccinia virus infected human monocyte derived macrophages

Journal of Inflammation, 2005
Background Viruses remain one of the inducers of the stress response in the infected cells. Heat shock response induced by vaccinia virus (VV) infection was studied in vitro in human blood monocyte derived macrophages (MDMs) as blood cells usually ...
Dziedzic Jakub, Slezak Kinga, Guzik Krzysztof, Kowalczyk Aleksandra, Rokita Hanna   +4 more
doaj   +1 more source

Absence of ataxin-3 leads to enhanced stress response in C. elegans. [PDF]

PLoS ONE, 2011
Ataxin-3, the protein involved in Machado-Joseph disease, is able to bind ubiquitylated substrates and act as a deubiquitylating enzyme in vitro, and it has been involved in the modulation of protein degradation by the ubiquitin-proteasome pathway.
Ana João Rodrigues, Andreia Neves-Carvalho, Andreia Teixeira-Castro, Anne Rokka, Garry Corthals, Elsa Logarinho, Patrícia Maciel   +6 more
doaj   +1 more source

Candidate stress biomarkers for queen failure diagnostics

BMC Genomics, 2020
Background Queen failure is a persistent problem in beekeeping operations, but in the absence of overt symptoms it is often difficult, if not impossible, to ascertain the root cause. Stressors like heat-shock, cold-shock, and sublethal pesticide exposure
Alison McAfee, Joseph Milone, Abigail Chapman, Leonard J. Foster, Jeffery S. Pettis, David R. Tarpy   +5 more
doaj   +1 more source

The heat shock response in neurons and astroglia and its role in neurodegenerative diseases

Molecular Neurodegeneration, 2017
Protein inclusions are a predominant molecular pathology found in numerous neurodegenerative diseases, including amyotrophic lateral sclerosis and Huntington’s disease.
Rebecca San Gil, Lezanne Ooi, Justin J. Yerbury, Heath Ecroyd   +3 more
doaj   +1 more source