Results 151 to 160 of about 211,605 (257)

Human milk-derived extracellular vesicles promote the heat shock response in polarized microglia. [PDF]

Cell Stress Chaperones
Storm JA, Lu J, Obtial MF, Wijenayake S.
europepmc   +1 more source

Inducible transcriptional condensates drive 3D genome reorganization in the heat shock response. [PDF]

Mol Cell, 2022
Chowdhary S, Kainth AS, Paracha S, Gross DS, Pincus D.   +4 more
europepmc   +1 more source

A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells

Advanced Science, EarlyView.
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong, Ziwei Zhang, Ao Li, Ting Sun, Yunzhao Wu, Devkee M. Vadukul, Dylan Jones, Bing Li, Fengjie Liu, Francesco A. Aprile, Yuri Korchev, Julia Gorelik, David Klenerman, Andrew Shevchuk   +13 more
wiley   +1 more source

eIF3g binding to GUCG boxes located in mRNA coding regions enhances translation of mild heat shock response genes in the yeast Saccharomyces cerevisiae. [PDF]

Nucleic Acids Res
Kato H, Oguro A, Mao Y, Ochsner K, Casey H, Sakai G, Wan J, Usuki S, Tang L, Asano M, Bardiya N, Kaufman K, Ishiguro S, Tani N, Kumagai K, Nakamura A, Singh CR, Sakamoto T, Obayashi E, Qian SB, Asano K.   +20 more
europepmc   +1 more source

Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1-mediated heat shock response. [PDF]

PLoS Biol, 2023
Miles J, Townend S, Milonaitytė D, Smith W, Hodge F, Westhead DR, van Oosten-Hawle P.   +6 more
europepmc   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Response and adaptation of the transcriptional heat shock response to pressure. [PDF]

Front Microbiol
Coffin CH, Fisher LA, Crippen S, Demers P, Bartlett DH, Royer CA.   +5 more
europepmc   +1 more source

Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response. [PDF]

Pharm Biol, 2022
Shen Q, Chen Q, Liu Y, Xue X, Shen X, He Q, Wang G, Han F.   +7 more
europepmc   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

The heat shock response in plants: new insights into modes of perception, signaling, and the contribution of hormones. [PDF]

J Exp Bot
Dündar G, Ramirez VE, Poppenberger B.
europepmc   +1 more source