Results 151 to 160 of about 211,923 (255)

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

open access: yesAdvanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li   +5 more
wiley   +1 more source

Response and adaptation of the transcriptional heat shock response to pressure. [PDF]

open access: yesFront Microbiol
Coffin CH   +5 more
europepmc   +1 more source

Inducible transcriptional condensates drive 3D genome reorganization in the heat shock response. [PDF]

open access: yesMol Cell, 2022
Chowdhary S   +4 more
europepmc   +1 more source

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng   +8 more
wiley   +1 more source

eIF3g binding to GUCG boxes located in mRNA coding regions enhances translation of mild heat shock response genes in the yeast Saccharomyces cerevisiae. [PDF]

open access: yesNucleic Acids Res
Kato H   +20 more
europepmc   +1 more source

Two-step model of paleohexaploidy, ancestral genome reshuffling and plasticity of heat shock response in Asteraceae. [PDF]

open access: yesHortic Res, 2023
Kong X   +16 more
europepmc   +1 more source

Origami Metamaterials Based on Low‐Melting‐Point Alloy Phase Transition: Breaking the Trade‐Off Between Reusability and Energy Absorption Quality

open access: yesAdvanced Science, EarlyView.
This work presents an origami metamaterial that integrates a low‐melting‐point alloy skeleton into an elastomeric shell. It dissipates energy through the metal's plastic deformation and recovers through the solid–liquid phase transition of the alloy together with the hyperelasticity of the shell.
Yupeng Liu   +5 more
wiley   +1 more source

Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1-mediated heat shock response. [PDF]

open access: yesPLoS Biol, 2023
Miles J   +6 more
europepmc   +1 more source

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