Results 31 to 40 of about 870,730 (334)

RNAi based transcriptome suggests genes potentially regulated by HSF1 in the Pacific oyster Crassostrea gigas under thermal stress

open access: yesBMC Genomics, 2019
Background The Pacific oyster Crassostrea gigas is an important fishery resource that is sensitive to temperature fluctuations. Thus, it has evolved a protection mechanism against heat stress by increasing the expression of the gene coding for heat shock
Youli Liu   +4 more
doaj   +1 more source

Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor

open access: yesFrontiers in Microbiology, 2022
Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living bacteria, the transcriptomic reprogramming is mediated by increased DNA-binding activity of heat shock sigma factors and activation of genes normally repressed ...
Yehong Huang   +12 more
doaj   +1 more source

Cold Shock Response in Bacteria.

open access: yesAnnual Review of Genetics, 2021
Bacteria often encounter temperature fluctuations in their natural habitats and must adapt to survive. The molecular response of bacteria to sudden temperature upshift or downshift is termed the heat shock response (HSR) or the cold shock response (CSR),
Yan Zhang, C. Gross
semanticscholar   +1 more source

Heat shock proteins in health and disease: therapeutic targets or therapeutic agents? [PDF]

open access: yes, 2001
For many years, heat shock or stress proteins have been regarded as intracellular molecules that have a range of housekeeping and cytoprotective functions, only being released into the extracellular environment in pathological situations such as necrotic
Pockley, A.G.
core   +1 more source

Biomarker Exploration in Human Peripheral Blood Mononuclear Cells for Monitoring Sulforaphane Treatment Responses in Autism Spectrum Disorder [PDF]

open access: yes, 2020
Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders with no drugs treating the core symptoms and no validated biomarkers for clinical use.
Connors, Susan L.   +7 more
core   +3 more sources

Dynamic m6A mRNA methylation directs translational control of heat shock response

open access: yesNature, 2015
The most abundant mRNA post-transcriptional modification is N6-methyladenosine (m6A), which has broad roles in RNA biology. In mammalian cells, the asymmetric distribution of m6A along mRNAs results in relatively less methylation in the 5′ untranslated ...
Jun Zhou   +4 more
semanticscholar   +1 more source

Lack of an HSP70 heat shock response in two Antarctic marine invertebrates [PDF]

open access: yes, 2008
Members of the HSP70 gene family comprising the inducible (HSP70) genes and GRP78 (glucose-regulated protein 78 kDa) were identified in an Antarctic sea star (Odontaster validus) and an Antarctic gammarid (Paraceradocus gibber). These genes were surveyed
Clark, Melody S.   +2 more
core   +2 more sources

Heat Shock Response - Pathophysiological Implications

open access: yesAnnals of Medicine, 1997
All organisms exposed to environmental stress conditions share a common molecular response characterized by a dramatic change in the pattern of gene expression followed by an elevated synthesis of heat shock or stress proteins. These proteins function as molecular chaperones to protect cells from environmental stress damage by binding to partially ...
S, Leppä, L, Sistonen
openaire   +2 more sources

Identifying gene regulatory modules of heat shock response in yeast

open access: yesBMC Genomics, 2008
Background A gene regulatory module (GRM) is a set of genes that is regulated by the same set of transcription factors (TFs). By organizing the genome into GRMs, a living cell can coordinate the activities of many genes in response to various internal ...
Li Wen-Hsiung, Wu Wei-Sheng
doaj   +1 more source

Use of fine unheated wires in shock tubes [PDF]

open access: yes, 1960
Some preliminary measurements of heat transfer to fine unheated wires have been made in the shock tube.
Christiansen, Walter H.
core   +1 more source

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