The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review
Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses.
Ariadni Androvitsanea +3 more
doaj +3 more sources
The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. [PDF]
The heat shock response, the cellular response to protein damaging stress, is critical in maintaining proteostasis. The heat shock response is regulated by the transcription factor HSF1, which is activated upon heat shock and other stresses to induce the
Rachel Raynes +5 more
doaj +3 more sources
Dynamic global acetylation remodeling during the yeast heat shock response [PDF]
Background All organisms experience stress and must rapidly respond to changing conditions. Thus, cells have evolved sophisticated rapid-response mechanisms such as post-translational protein modification to rapidly and reversibly modulate protein ...
Rebecca E. Hardman-Kavanaugh +12 more
doaj +2 more sources
Transcriptional and translational dynamics underlying heat shock response in the thermophilic crenarchaeon Sulfolobus acidocaldarius [PDF]
High-temperature stress is critical for all organisms and induces a profound cellular response. For Crenarchaeota, little information is available on how heat shock affects cellular processes and on how this response is regulated.
Rani Baes +10 more
doaj +2 more sources
Unveiling the novel regulatory roles of RpoD-family sigma factors in Salmonella Typhimurium heat shock response through systems biology approaches. [PDF]
Three RpoD-family sigma factors, RpoD, RpoS, and RpoH, play critical roles in transcriptional regulation in Salmonella enterica serovar Typhimurium under heat shock conditions.
Joon Young Park +5 more
doaj +2 more sources
Lack of peroxisomal catalase affects heat shock response in Caenorhabditis elegans
The authors present a previously unknown crosstalk between peroxisomes and the heat shock response, whereby the peroxisomal catalase is vital for cellular capacity to survive heat stress and undergo heat-induced lifespan extension.
Marina Musa +5 more
doaj +1 more source
The heat shock response and small molecule regulators. [PDF]
Kurop MK +4 more
europepmc +2 more sources
Background Psychrotrophic lactic acid bacteria (LAB) species are the dominant species in the microbiota of cold-stored modified-atmosphere-packaged food products and are the main cause of food spoilage. Despite the importance of psychrotrophic LAB, their
Ilhan Cem Duru +5 more
doaj +1 more source
Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study [PDF]
BACKGROUND AND PURPOSE: Previous work has shown that soluble heat shock protein 60 (HSP60; sHSP60), present in circulating blood, is associated with carotid atherosclerosis.
XIAO, Q +8 more
core +5 more sources
Transient intracellular acidification regulates the core transcriptional heat shock response
Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thought ...
Catherine G Triandafillou +3 more
doaj +1 more source

