Results 31 to 40 of about 569,417 (300)

Biomarker Exploration in Human Peripheral Blood Mononuclear Cells for Monitoring Sulforaphane Treatment Responses in Autism Spectrum Disorder [PDF]

, 2020
Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders with no drugs treating the core symptoms and no validated biomarkers for clinical use.
Connors, Susan L., Diggins, Eileen, Dinkova-Kostova, Albena, Fahey, Jed W., Liu, Hua, Singh, Kanwaljit, Stephenson, Katherine K., Zimmerman, Andrew W.   +7 more
core   +3 more sources

Heat shock response relieves ER stress [PDF]

The EMBO Journal, 2008
Accumulation of misfolded protein in the endoplasmic reticulum (ER) causes stress. The unfolded protein response (UPR), a transcriptional induction pathway, is activated to relieve ER stress. Although UPR is not essential for viability, UPR-deficient cells are more sensitive to ER stress; ire1Delta cells cannot grow when challenged with tunicamycin or ...
Liu, Yu, Chang, Amy
openaire   +3 more sources

Identifying gene regulatory modules of heat shock response in yeast

BMC Genomics, 2008
Background A gene regulatory module (GRM) is a set of genes that is regulated by the same set of transcription factors (TFs). By organizing the genome into GRMs, a living cell can coordinate the activities of many genes in response to various internal ...
Li Wen-Hsiung, Wu Wei-Sheng
doaj   +1 more source

The Heat Shock Response in the Western Honey Bee (Apis mellifera) is Antiviral

Viruses, 2020
Honey bees (Apis mellifera) are an agriculturally important pollinator species that live in easily managed social groups (i.e., colonies). Unfortunately, annual losses of honey bee colonies in many parts of the world have reached unsustainable levels ...
Alexander J. McMenamin, Katie F. Daughenbaugh, Michelle L. Flenniken   +2 more
doaj   +1 more source

Use of fine unheated wires in shock tubes [PDF]

, 1960
Some preliminary measurements of heat transfer to fine unheated wires have been made in the shock tube.
Christiansen, Walter H.
core   +1 more source

Diversification of the Caenorhabditis heat shock response by Helitron transposable elements. [PDF]

, 2019
Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress ...
Ahringer, Altschul, Ashe, Bailey, Bourque, Brunquell, Casper, Cavrak, Christians, Chuong, Chuong, Contrino, Cook, Cook, Cutter, Esnault, Feschotte, Fierst, Fuentes, Gonsalves, Grabundzija, Grant, Guertin, Gupta, Halfon, Ho, Howe, Howe, Huang, Huang, Hubley, Ito, Jedlicka, Jiang, Johnstone, Jordan, Kanzaki, Kapitonov, Kapitonov, Kent, Kojima, Labbadia, Langmead, Lee, Li, Li, Li, Liu, Love, Mahat, Maman, Mao, Mark, Matys, McClintock, Mendillo, Mortazavi, Narasimhan, Narasimhan, Patro, Perisic, Pontis, R Development Core Team, Rausch, Santos, Schreiner, Shirayama, Slos, Slotkin, Solís, Stevens, Sun, Sundaram, Sundaram, Tajima, Takaki, Thomas, Thomas, Thomas, Todd, Verster, Vihervaara, Weirauch, Wood, Zhang   +84 more
core   +2 more sources

YoeB toxin is activated during thermal stress. [PDF]

, 2015
Type II toxin-antitoxin (TA) modules are thought to mediate stress-responses by temporarily suppressing protein synthesis while cells redirect transcription to adapt to environmental change.
Garza-Sánchez, Fernando, Hayes, Christopher S, Janssen, Brian D   +2 more
core   +1 more source

Regulation of the Heat-Shock Response [PDF]

Plant Physiology, 1998
The heat-shock response is a conserved reaction of cells and organisms to elevated temperatures (heat shock or heat stress). Whereas severe heat stress leads to cellular damage and cell death, sublethal doses of heat stress induce a cellular response, the heat-shock response, which (a ...
F, Schöffl, R, Prändl, A, Reindl
openaire   +2 more sources

Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line

Journal of Inflammation, 2011
Poly (ADP-ribose) polymerase-1 (PARP-1) is a highly conserved multifunctional enzyme, and its catalytic activity is stimulated by DNA breaks. The activation of PARP-1 and subsequent depletion of nicotinamide adenine dinucleotide (NAD+) and adenosine ...
Zingarelli Basilia, Gefter Julia V, Sjodin Hanna, Aneja Rajesh K, Delude Russell L   +4 more
doaj   +1 more source

Heat Shock Response and Heat Shock Proteins: Current Understanding and Future Opportunities in Human Diseases. [PDF]

Int J Mol Sci
Singh MK, Shin Y, Ju S, Han S, Choe W, Yoon KS, Kim SS, Kang I.   +7 more
europepmc   +2 more sources