Results 41 to 50 of about 870,730 (334)
Heat shock response relieves ER stress [PDF]
The EMBO Journal, 2008 Accumulation of misfolded protein in the endoplasmic reticulum (ER) causes stress. The unfolded protein response (UPR), a transcriptional induction pathway, is activated to relieve ER stress. Although UPR is not essential for viability, UPR-deficient cells are more sensitive to ER stress; ire1Delta cells cannot grow when challenged with tunicamycin or ...
Liu, Yu, Chang, Amy
openaire +3 more sources
YoeB toxin is activated during thermal stress. [PDF]
, 2015 Type II toxin-antitoxin (TA) modules are thought to mediate stress-responses by temporarily suppressing protein synthesis while cells redirect transcription to adapt to environmental change.
Garza-Sánchez, Fernando +2 more
core +1 more source
Proteotoxic stress reprograms the chromatin landscape of SUMO modification [PDF]
, 2015 The small ubiquitin-like modifier 2 (SUMO-2) is required for survival when cells are exposed to treatments that induce proteotoxic stress by causing the accumulation of misfolded proteins.
Anne Seifert +4 more
core +3 more sources
Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response
bioRxiv, 2017 Models for regulation of the eukaryotic heat shock response typically invoke a negative feedback loop consisting of the transcriptional activator Hsf1 and a molecular chaperone encoded by an Hsf1 target gene.
Joanna Krakowiak +7 more
semanticscholar +1 more source
Journal of Inflammation, 2011 Poly (ADP-ribose) polymerase-1 (PARP-1) is a highly conserved multifunctional enzyme, and its catalytic activity is stimulated by DNA breaks. The activation of PARP-1 and subsequent depletion of nicotinamide adenine dinucleotide (NAD+) and adenosine ...
Zingarelli Basilia +4 more
doaj +1 more source
Heat shock proteins and the cellular response to osmotic stress [PDF]
, 2000 In antidiuresis, the intrarenal distribution of HSP25/27, alpha beta -crystallin, HSP72, OSP94 and HSP110 corresponds to the osmotic gradient between cortex and papilla: low amounts in the cortex and high values in the inner medulla and papilla.
Beck, Franz-X. +3 more
core +1 more source
Frontiers in Plant Science, 2021 Heat stress events are major factors limiting crop productivity. During summer days, land plants must anticipate in a timely manner upcoming mild and severe temperature.
Baptiste Bourgine, A. Guihur
semanticscholar +1 more source
Transient intracellular acidification regulates the core transcriptional heat shock response
bioRxiv, 2018 Cellular stress induces rapid expression of genes encoding molecular chaperones. In many eukaryotes, stress also triggers transient intracellular acidification which, by unknown mechanisms, is associated with increased survival. Here, using budding yeast
Catherine G. Triandafillou +3 more
semanticscholar +1 more source
Regulation of the Heat-Shock Response [PDF]
Plant Physiology, 1998 The heat-shock response is a conserved reaction of cells and organisms to elevated temperatures (heat shock or heat stress). Whereas severe heat stress leads to cellular damage and cell death, sublethal doses of heat stress induce a cellular response, the heat-shock response, which (a ...
F, Schöffl, R, Prändl, A, Reindl
openaire +2 more sources
Heat shock stimulation of a tilapia heat shock protein 70 promoter is mediated by a distal element [PDF]
, 2001 peer reviewedWe reported previously that a tilapia (Oreochromis mossambicus) heat shock protein 70 (HSP70) promoter is able to confer heat shock response on a reporter gene after transient expression both in cell culture and in microinjected zebrafish ...
Di Martino, Emmanuel +3 more
core +2 more sources