Results 61 to 70 of about 171,650 (268)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Partial abdominal carbon-ion FLASH irradiation spares lethality compared to conventional irradiation: impact of LET and dose rate

Radiation Oncology
Background Ultra-high dose rate (FLASH) therapy has attracted attention for its potential to effectively target tumors while preserving healthy tissues.
Wenteng Cao, Yukari Yoshida, Hiromu Suda, Shunsuke Inagaki, Naoto Urabe, Masao Nakao, Ken Yusa, Xiangdi Meng, Mutsumi Tashiro, Akihisa Takahashi, Tatsuya Ohno   +10 more
doaj   +1 more source

A retrospective study of adjuvant proton radiotherapy for breast cancer after lumpectomy: a comparison of conventional-dose and hypofractionated dose

Radiation Oncology, 2023
Purpose This study aimed to compare the adverse reactions of conventional-dose and hypofractionated dose of proton therapy for breast cancer. Materials and methods Breast cancer patients treated with proton radiotherapy in conventional-dose or ...
ZhengShan Hong, ZhaoZhi Yang, Xin Mei, Ping Li, Cihang Bao, Zheng Wang, Xin Cai, Xue Ming, WeiWei Wang, XiaoMao Guo, XiaoLi Yu, Qing Zhang   +11 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Heavy Ion Collisions

, 2004
Lattice QCD predicts a phase transition between hadronic matter and a system of deconfined quarks and gluons (the Quark Gluon Plasma) at high energy densities. Recent results from the Brookhaven Relativistic Heavy Ion Collider (RHIC) dedicated to the study of QCD at extreme densities will be discussed and compared to measurements obtained at the CERN ...
openaire   +4 more sources

Customized mouthpieces designed to reduce tongue mucositis in carbon-ion radiotherapy for tumors of the nasal and paranasal sinuses

Physics and Imaging in Radiation Oncology, 2017
Mouthpieces are used to fix the positions of the lower jaw and teeth during carbon-ion radiotherapy for head and neck tumors. We used a customized mouthpiece to reduce radiation mucositis by displacing the tongue.
Atsushi Musha, Jun-ichi Saitoh, Katsuyuki Shirai, Yoshiki Kubota, Hirofumi Shimada, Takanori Abe, Yuka Komatsu, Shuichiro Komatsu, Tatsuya Ohno, Takashi Nakano, Satoshi Yokoo   +10 more
doaj   +1 more source

Performance of a 6D Treatment Chair for Patient Positioning in an Upright Posture for Fixed Ion Beam Lines

Frontiers in Oncology, 2020
Purpose: To evaluate the mechanical accuracy and the robustness of position alignment under x-ray-based image guidance of a treatment chair with six degrees of freedom (6DTC) which was developed for patient treatment in an upright posture at fixed ...
Yinxiangzi Sheng, Yinxiangzi Sheng, Jiayao Sun, Jiayao Sun, Weiwei Wang, Weiwei Wang, Brian Stuart, Lin Kong, Lin Kong, Jing Gao, Jing Gao, Dan You, Dan You, Xiaodong Wu, Xiaodong Wu   +14 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source