Results 121 to 130 of about 65,792 (310)
Advanced Science, EarlyView.A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo +13 more
wiley +1 more source
Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
Advanced Science, EarlyView.ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
A Comparison of Methods for Estimating the Tail Index of Heavy-tailed Internet Traffic
Many researchers have discussed the effects of heavy-tailedness in network traffic patterns and shown that Internet traffic flows exhibit characteristics of self-similarity that can be explained by the heavy-tailedness of the various distributions ...
Mohammed Rezaul, Karim +3 more
core +1 more source
ANALYSIS OF ALSELMANI SIGNALIZED INTERSECTION IN BENGHAZI - LIBYA [PDF]
, 2013 Intersections play an important role in the road network, where traffic flows in different directions converge. Because of their influence each other, disturbance of pedestrians and bicycle to vehicles, and the lost of green time for beginning and ...
core
Advanced Science, EarlyView.Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang +17 more
wiley +1 more source
Evaluation of Different Methods to Calculate Heavy-Truck VMT, Final Report, December 2004
, 2004 Reliable estimates of heavy-truck volumes are important in a number of transportation applications. Estimates of truck volumes are necessary for pavement design and pavement management. Truck volumes are important in traffic safety.
core
Metasurface‐Enabled Active‐Like Passive Radar
Advanced Science, EarlyView.A programmable space‐time‐coding metasurface embeds distinct spatiotemporal tags into ambient wireless signals, allowing passive radar to operate in an active‐like manner. By enabling code‐correlated reconstruction under interference, the approach supports robust real‐time UAV tracking in complex environments and points to intelligent, low‐power ...
Mingyi Li +7 more
wiley +1 more source
Reflecting Brownian motion in two dimensions: Exact asymptotics for the stationary distribution
Stochastic Systems, 2011 We consider a two-dimensional semimartingale reflecting Brownian motion (SRBM) in the nonnegative quadrant. The data of the SRBM consists of a two-dimensional drift vector, a 2 × 2 positive definite covariance matrix, and a 2 × 2 reflection matrix ...
Jim Dai, Masakiyo Miyazawa
doaj
HUMAN HEALTH RISK ASSESSMENT: A CASE STUDY OF HEAVY METAL CONTAMINATION OF GARDEN SOILS IN SZEGED [PDF]
Acta Geographica Debrecina. Landscape & Environment Series, 2009 The soils of the big cities, owing to the various anthropogenic activities, can be contaminated by heavy metals. The surroundings of the roads with heavy traffic as significant metal emitter source can be contaminated by heavy metals.
ANDREA FARSANG +2 more
doaj
Oligopeptides/DNA Coacervate Droplets as Macromolecular Delivery Microcarriers
Advanced Science, EarlyView.Oligopeptide–DNA coacervates formed via liquid–liquid phase separation serve as programmable carriers for macromolecular cargos, entering cells through lipid raft–associated pathways and subsequently undergoing enzyme triggered intracellular disassembly driven by DNA degradation processes, thereby enabling efficient, controlled, and spatially defined ...
Linyi Zhang +5 more
wiley +1 more source