Results 41 to 50 of about 74,143 (263)
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
wiley +1 more source
For a real function \(f\) of class \({\mathcal C}^2\) on the unit sphere \(\mathbb{S}^n\) of Euclidean space \((\mathbb{R}^{n+1}, \langle\cdot, \cdot\rangle)\), the hedgehog with support function \(f\) is the parametrized surface (in general with singularities) \(x_f:\mathbb{S}^n \to\mathbb{R}^{n+1}\) with \(x_f(u)= f(u)u+ (\text{grad} f)(u)\); thus it
openaire +2 more sources
Exotic pets, including hedgehogs, have become popular in recent years among pet owners, especially in North America. Such animals can carry and introduce zoonotic agents, a fact well illustrated by the recent outbreak of monkeypox in pet prairie dogs.
Patricia Y. Riley, Bruno B. Chomel
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Flexoelectrically Induced Polar Topology in Twisted SrTiO3 Membranes
Twisted SrTiO3 bilayers host polar vortices of flexoelectric origin, revealed through combined experiment and theory. By reconstructing polarization from the toroidal moment of strain gradients, the work establishes a 3D chiral state with broken inversion and mirror symmetries.
Isabel Tenreiro +13 more
wiley +1 more source
Abstract Hepatocellular adenomas (HCAs) are benign liver tumors associated with bleeding or malignant transformation. Data on the indication for surgery are scarce. We analyzed indications and outcome of patients operated for HCAs < 50 mm compared to HCAs ≥ 50 mm. Changes in final postoperative diagnosis were assessed.
Martijn P. D. Haring +70 more
wiley +1 more source
Hedgehog-GLI (HH) signaling was originally identified as a critical morphogenetic pathway in embryonic development. Since its discovery, a multitude of studies have reported that HH signaling also plays key roles in a variety of cancer types and in ...
Silvia Pietrobono, Barbara Stecca
doaj +1 more source
IN NATURE of May 19 last (pp. 375–76) you were good enough to notice at length my paper on “The Ancient Legend as to the Hedgehog carrying Fruit upon its Spines,“ published by the Manchester Literary and Philosophical Society (Memoirs, vol. 63, No. 2). That paper was written with a view to elicit further evidence for or against the truth of the legend,
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Multimodal Human–Robot Interaction Using Human Pose Estimation and Local Large Language Models
A multimodal human–robot interaction framework integrates human pose estimation (HPE) and a large language model (LLM) for gesture‐ and voice‐based robot control. Speech‐to‐text (STT) enables voice command interpretation, while a safety‐aware arbitration mechanism prioritizes gesture input for rapid intervention.
Nasiru Aboki +2 more
wiley +1 more source
Hedgehog Signaling in Gonadal Development and Function
Three distinct hedgehog (HH) molecules, (sonic, desert, and indian), two HH receptors (PTCH1 and PTCH2), a membrane bound activator (SMO), and downstream three transcription factors (GLI1, GLI2, and GLI3) are the major components of the HH signaling ...
Iman Dilower +5 more
doaj +1 more source
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu +14 more
wiley +1 more source

