Results 31 to 40 of about 74,143 (263)
Molecules, 2019 Sonic hedgehog (Shh) signaling plays a tumor-promoting role in many epithelial cancers. Cancer cells produce soluble a Shh that signals to distant stromal cells that express the receptor Patched (Ptc).
Dominique Manikowski +3 more
doaj +1 more source
Case Report: Metastatic renal giant-cell sarcoma in an African pygmy hedgehog (Atelerix albiventris)
Frontiers in Veterinary ScienceThe scientific literature referring to tumors in African pygmy hedgehog (Atelerix albiventris) is expanding, enhanced by an increased lifespan under human care.
Pablo Díaz-Santana +3 more
doaj +1 more source
Frontiers in Oncology, 2020 Background: Craniofacial osteosarcomas (COS) and extracranial osteosarcomas (EOS) show distinct clinical differences. COS show a remarkably lower incidence of metastases and a better survival.
Manuel Weber +6 more
doaj +1 more source
COVID‐19 lockdown measures impacted citizen science hedgehog observation numbers in Bavaria, Germany
Ecology and Evolution, 2022 The COVID‐19 pandemic has led to temporary changes in human–animal interactions due to changes in human activities. Here, we report on a surge in hedgehog observations during the first COVID‐19 lockdown in Germany in 2020, on the citizen science Web ...
Fabio S. T. Sweet +2 more
doaj +1 more source
Journal of Fungi, 2021 The rising number of European hedgehogs (Erinaceus europaeus) admitted every year to wildlife rehabilitation centres might be a source of concern to animal and public health since transmissible diseases, such as dermatophytosis, can be easily ...
Cécile Le Barzic +6 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Invasive Urban Mammalian Predators: Distribution and Multi-Scale Habitat Selection
Biology, 2022 A barrier to successful ecological restoration of urban green spaces in many cities is invasive mammalian predators. We determined the fine- and landscape-scale habitat characteristics associated with the presence of five urban predators (black and brown
Kim F. Miller +6 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: Nonalcoholic steatohepatitis (NASH), a leading cause of cirrhosis, strongly associates with the metabolic syndrome, an insulin-resistant proinflammatory state that disrupts energy balance and promotes progressive liver degeneration.
Tianyi Chen +14 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source