Results 11 to 20 of about 101,813 (256)

Hedgehog Signaling Modulates Glial Proteostasis and Lifespan

open access: yesCell Reports, 2020
Summary: The conserved Hedgehog signaling pathway has well-established roles in development. However, its function during adulthood remains largely unknown.
Andrew Rallis   +6 more
doaj   +2 more sources

The role of Sulf1 during Sonic hedgehog mediated neural patterning [PDF]

open access: yes, 2011
Heparan sulphate proteoglycans (HSPGs) are large molecules distributed ubiquitously, both at the cell surface and within the extracellular matrix. These molecules are known to play essential roles in developmental cell signalling, and the differential ...
Ramsbottom, Simon.A
core   +6 more sources

gatoravi/hedgehog-variability:

open access: yes, 2022
v1.0.0 of the notebooks used in the hedgehog variability ...
Avinash R
core   +2 more sources

Morphological and histological study of the third eyelid in hedgehogs

open access: yesVeterinary Medicine and Science, 2023
Background The third eyelid in animals plays an important role in maintaining eye health. Like other organs of the body, the third eyelid can be afflicted with minor or deep injuries, inflammations or even tumours in different species.
Erfan Shakibapour, Mohammadreza Paryani
doaj   +1 more source

Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation [PDF]

open access: yes, 2009
We show that Indian Hedgehog (Ihh) regulates T-cell development and homeostasis in both fetal and adult thymus, controlling thymocyte number. Fetal Ihh-/- thymi had reduced differentiation to double-positive (DP) cell and reduced cell numbers compared ...
Outram, Susan V   +17 more
core   +1 more source

Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems [PDF]

open access: yes, 2007
PhDEmbryonic development is regulated by a number of signalling pathways, Which are critical for normal growth. Many of these genes then continue to play an important role in the regulation of cell growth and differentiation in adult.
Ikram, Mohammed S, Ikram, Mohammed. S.
core   +4 more sources

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]

open access: yes, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Henrich, Dirk   +5 more
core   +1 more source

Molecular Characterization of the Hedgehog Signaling Pathway and Its Necessary Function on Larval Myogenesis in the Pacific Oyster Crassostrea gigas

open access: yesFrontiers in Physiology, 2018
Hedgehog signaling pathway participates in a chain of necessary physiological activities and dysregulation of the hedgehog signaling has been implicated in birth defects and diseases.
Huijuan Li   +4 more
doaj   +1 more source

Hedgehogs and Hedgehog-Head Boats in Ancient Egyptian Religion in the Late 3rd Millennium BCE

open access: yesArts, 2022
Hedgehogs held a special place in ancient Egyptian life like many other desert- and marsh-dwelling animals. Their natural defensive qualities were admired by ancient Egyptians and their bodily parts, notably their hardened spines, were used as ...
Julia Clare Francis Hamilton
doaj   +1 more source

T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number

open access: yeseLife, 2016
Crucial roles for T-box3 in development are evident by severe limb malformations and other birth defects caused by T-box3 mutations in humans. Mechanisms whereby T-box3 regulates limb development are poorly understood.
Uchenna Emechebe   +6 more
doaj   +1 more source

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