Results 51 to 60 of about 92,604 (309)

Detection and Control of Dermatophytosis in Wild European Hedgehogs (Erinaceus europaeus) Admitted to a French Wildlife Rehabilitation Centre

open access: yesJournal of Fungi, 2021
The rising number of European hedgehogs (Erinaceus europaeus) admitted every year to wildlife rehabilitation centres might be a source of concern to animal and public health since transmissible diseases, such as dermatophytosis, can be easily ...
Cécile Le Barzic   +6 more
doaj   +1 more source

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect

open access: yes, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Henrich, Dirk   +5 more
core   +1 more source

Case Report: Metastatic renal giant-cell sarcoma in an African pygmy hedgehog (Atelerix albiventris)

open access: yesFrontiers in Veterinary Science
The scientific literature referring to tumors in African pygmy hedgehog (Atelerix albiventris) is expanding, enhanced by an increased lifespan under human care.
Pablo Díaz-Santana   +3 more
doaj   +1 more source

Invasive Urban Mammalian Predators: Distribution and Multi-Scale Habitat Selection

open access: yesBiology, 2022
A barrier to successful ecological restoration of urban green spaces in many cities is invasive mammalian predators. We determined the fine- and landscape-scale habitat characteristics associated with the presence of five urban predators (black and brown
Kim F. Miller   +6 more
doaj   +1 more source

Habits of the Hedgehog [PDF]

open access: yesNature, 1921
IN NATURE of May 19 last (pp. 375–76) you were good enough to notice at length my paper on “The Ancient Legend as to the Hedgehog carrying Fruit upon its Spines,“ published by the Manchester Literary and Philosophical Society (Memoirs, vol. 63, No. 2). That paper was written with a view to elicit further evidence for or against the truth of the legend,
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver DiseaseSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: Nonalcoholic steatohepatitis (NASH), a leading cause of cirrhosis, strongly associates with the metabolic syndrome, an insulin-resistant proinflammatory state that disrupts energy balance and promotes progressive liver degeneration.
Tianyi Chen   +14 more
doaj   +1 more source

The role of Sulf1 during Sonic hedgehog mediated neural patterning [PDF]

open access: yes, 2011
Heparan sulphate proteoglycans (HSPGs) are large molecules distributed ubiquitously, both at the cell surface and within the extracellular matrix. These molecules are known to play essential roles in developmental cell signalling, and the differential ...
Ramsbottom, Simon A, Ramsbottom, Simon.A
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Hedgehog Zoonoses

open access: yesEmerging Infectious Diseases, 2005
Exotic pets, including hedgehogs, have become popular in recent years among pet owners, especially in North America. Such animals can carry and introduce zoonotic agents, a fact well illustrated by the recent outbreak of monkeypox in pet prairie dogs.
Patricia Y. Riley, Bruno B. Chomel
openaire   +3 more sources

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