Results 171 to 180 of about 2,340,031 (328)

Antbears and underground melons: A highly specialized seed dispersal mutualism mediated by scent

PLANTS, PEOPLE, PLANET, EarlyView.
Seed dispersal is critical for the establishment and persistence of populations of most plant species. We investigated the seed dispersal biology of an African melon, Cucumis humifructus, which is closely related to cultivated cucumbers and watermelons but differs in that it buries its fruits deep underground.
Steven D. Johnson, Anka Eichhoff, Jeremy J. Midgley   +2 more
wiley   +1 more source

Massive Infiltrative Osteolysis of the Mandible in Oral Squamous Cell Carcinoma: A Case Report with a Review of the Literature

Precision Radiation Oncology, EarlyView.
Abstract Oral Squamous Cell Carcinoma (OSCC) is the most prevalent form of oral cancer, constituting over 90% of reported cases. This malignancy commonly infiltrates bone, making bone invasion a significant clinical issue. OSCC may invade bone via either an infiltrative or erosive pattern, with the pattern of invasion closely correlating with the ...
Smrithy Sivadas K, Ananya Madiyal, Vidya Ajila, Krishna Sharan, Yashika Jain   +4 more
wiley   +1 more source

Hedgehog and Fgf signaling pathways regulate the development of tphR‐expressing serotonergic raphe neurons in zebrafish embryos [PDF]

, 2004
Hiroki Teraoka, Claire Russell, Jennifer C. Regan, Anand Chandrasekhar, Miguel L. Concha, R Yokoyama, Kyohei Higashi, Masaru Takeuchi, Wenqi Dong, Takeo Hiraga, Nakisha D. Holder, Stephen W. Wilson   +11 more
openalex   +1 more source

Native and Engineered Extracellular Vesicles for the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome

Small Science, EarlyView.
Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu, Wenjun Xue, Guanchao Mao, Zhipeng Pei, Jingjing Li, Mingxue Sun, Xinkang Zhang, Shanshan Zhang, Songling Li, Jinfeng Cen, Kai Xiao, Ying Lu, Qingqiang Xu   +12 more
wiley   +1 more source

Investigational agents in metastatic basal cell carcinoma: focus on vismodegib

Journal of Experimental Pharmacology, 2012
Nicolas Batty,1 Ellen Kossoff,2 Grace K Dy11Department of Medicine, Roswell Park Cancer Center, Buffalo, NY, USA; 2Department of Pharmacy, Roswell Park Cancer Center, Buffalo, NY, USAAbstract: Vismodegib (GDC-0449, 2-chloro-N-(4-chloro-3-(pyridin-2-yl ...
Batty N, Kossoff E, Dy GK
doaj  

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

Small Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai, Jiawen Wang, Zihuan Lin, Danni Yu, Hui Yang, Jinsong Wei, Xiaoyu Li, Hao Hu, Chao Ni, Bing Zhao   +9 more
wiley   +1 more source

Long-range sclerotome induction by sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway

, 1995
Chen‐Ming Fan, Jeffery A. Porter, Chin Chiang, David T. Chang, Philip A. Beachy, Marc Tessier‐Lavigne   +5 more
openalex   +1 more source

Micro/Nanorobotics in Environmental Water Governance: Nanoengineering Strategies for Pollution Control

Small Structures, EarlyView.
Micro/nanorobots have been developed and deployed, revealing their state‐of‐the‐art applications in pollution detection and remediation. Innovative research progress includes collective behaviors, advanced propulsion mechanisms, and functionalization strategies that enhance their efficiency in diverse and complex aquatic environments, pointing toward ...
Yingyi Gan, Bin Wang, Yuan Lu
wiley   +1 more source

The Sonic Hedgehog–Patched–Gli Pathway in Human Development and Disease

, 2000
Elisabeth H. Villavicencio, David Walterhouse, Philip Iannaccone   +2 more
openalex   +1 more source

Medulloblastoma: mouse models and novel targeted therapies based on the Sonic hedgehog pathway [PDF]

, 2005
Leandro R. Piedimonte, Ian K. Wailes, Howard L. Weiner   +2 more
openalex   +1 more source