Results 251 to 260 of about 2,340,031 (328)
Developmental and epileptic encephalopathy in patients with epilepsy due to hypothalamic hamartomas
Epilepsia, EarlyView.Abstract Objective What factors influence cognition and behavior in patients with epilepsy caused by hypothalamic hamartoma (HH)? Methods We conducted a retrospective study of 103 patients referred to the Epilepsy Center in Freiburg, Germany, over the past 24 years.
Kathrin Wagner +9 more
wiley +1 more source
Dominant Activation of the Hedgehog Signaling Pathway in the Ovary Alters Theca Development and Prevents Ovulation [PDF]
, 2009 Yi Ren +3 more
openalex +1 more source
A review of the equine suspensory ligament: Injury prone yet understudied
Equine Veterinary Journal, EarlyView.Abstract The suspensory ligament (SL) is a key component of the elaborate and highly adapted suspensory apparatus in the horse. In addition to contributing to stabilisation of the metacarpophalangeal joint, the SL has a spring like function to reduce the energetic cost of locomotion.
Deborah J. Guest +2 more
wiley +1 more source
Inherited non‐syndromic polydactyly in a Berber and Arabian‐Berber horse family
Equine Veterinary Journal, EarlyView.Abstract Background Supernumerary digits, or polydactyly, have been described in various species including humans, wild and domestic animals. In horses, it represents the most common congenital limb malformation, which has only been described in isolated cases or nuclear families. Molecular aetiology has not been reported.
Ella Baville +7 more
wiley +1 more source
Osteochondrosis in horses: An overview of genetic and other factors
Equine Veterinary Journal, EarlyView.Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez +2 more
wiley +1 more source
Therapeutic targeting of TGF‐β in lung cancer
The FEBS Journal, Volume 292, Issue 7, Page 1520-1557, April 2025.Here, we discuss how lung cancer treatment can be transformed by targeting TGF‐β for better outcomes. Inhibiting TGF‐β signaling halts tumor growth, boosts immune response, and enhances treatment efficacy. By tackling TGF‐β's role in epithelial–mesenchymal transition (EMT) and immune evasion, this approach opens new avenues for more effective lung ...
Sajjad Aftabi +9 more
wiley +1 more source
Control of inflammation by stromal Hedgehog pathway activation restrains colitis
Proceedings of the National Academy of Sciences of the United States of America, 2016 John J. Lee +11 more
semanticscholar +1 more source
The FEBS Journal, Volume 292, Issue 9, Page 2173-2188, May 2025.Mitogen‐activated protein kinases (MAPKs) regulate various cellular processes, including proliferation, differentiation, and motility. Alterations in these signalling pathways can lead to various diseases, including cancer. The atypical MAPKs ERK3 (MAPK6), ERK4 (MAPK4), ERK7/8 (MAPK15) and NLK have long been neglected in kinomic studies.
Katrin Dahm +4 more
wiley +1 more source
Lawnmower Poetry and the Poetry of Lawnmowers
Critical Quarterly, EarlyView.
Francesca Gardner
wiley +1 more source
International Journal of Dermatology, EarlyView.ABSTRACT Background Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) represent clinicopathological variants of a spectrum. It is known that AFX and PDS tumors harbor frequent NOTCH1/2 mutations. However, the expression of Notch signaling pathway‐associated proteins in both tumor cells has not been studied before.
Yi‐Pei Lee +4 more
wiley +1 more source