Derlin2 Protein Facilitates HRD1-mediated Retro-translocation of Sonic Hedgehog at the Endoplasmic Reticulum [PDF]
, 2013 Chih‐Hsiang Huang +4 more
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Cell Proliferation, EarlyView.We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping +7 more
wiley +1 more source
Erratum to: High Expression of Sonic Hedgehog Signaling Proteins Is Related to the Favorable Outcome, EGFR Mutation, and Lepidic Predominant Subtype in Primary Lung Adenocarcinoma [PDF]
, 2013 Ji Eun Kim +5 more
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Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis
Cell Proliferation, EarlyView.Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang +9 more
wiley +1 more source
The Yes-associated protein controls the cell density regulation of Hedgehog signaling [PDF]
, 2014 Melanie Tariki +5 more
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JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and Objectives Dermatological oral antitumor therapeutics (OAT) are often interaction‐prone and used in complex regimens. The pharmacological/pharmaceutical care program of the randomized AMBORA trial significantly improved medication safety with various OAT; however, dermato‐oncological patients were not included.
Lisa Cuba +7 more
wiley +1 more source
Intraflagellar transport protein 122 is a novel antagonist of the murine Hedgehog signaling pathway
, 2008 Jian Qin, Yulian Lin, Hyuk-wan Ko
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Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein [PDF]
, 2014 Antonio D. Konitsiotis +6 more
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Inherited non‐syndromic polydactyly in a Berber and Arabian‐Berber horse family
Equine Veterinary Journal, EarlyView.Abstract Background Supernumerary digits, or polydactyly, have been described in various species including humans, wild and domestic animals. In horses, it represents the most common congenital limb malformation, which has only been described in isolated cases or nuclear families. Molecular aetiology has not been reported.
Ella Baville +7 more
wiley +1 more source