Results 261 to 270 of about 113,623 (349)

The GPR30 agonist G-1 promotes hair growth via Wnt/Hedgehog signaling in mice. [PDF]

Front Pharmacol
Yamano M, Yamanaka Y, Nishikawa S, Masujima Y, Ohue-Kitano R, Kimura I.   +5 more
europepmc   +1 more source

Adoption of artificial intelligence in healthcare: A strategic transformation framework

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 1, February 2026.
Abstract Background Artificial intelligence (AI) holds significant promise for transforming healthcare delivery, yet many AI initiatives fail to progress beyond pilot stages or achieve sustained system‐wide impact. These failures are rarely due to technical limitations alone, but instead reflect deeper challenges related to organisational readiness ...
Mattias Wei Ren Kon, John Abisheganaden, Gary Yee Ang   +2 more
wiley   +1 more source

Radiogenomics: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 2, February 2026.
Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang, Qingpei Lai, Jin Cao, Jerry Chi Fung Ching, Xinzhi Teng, Jiang Zhang, Shara Wee Yee Lee, Ge Ren, Jing Cai   +8 more
wiley   +1 more source

PRRX2 Regulates GLI2 to Promote Proliferation, Invasion, and Metastasis by Inhibiting Senescence via Hedgehog Signaling. [PDF]

Cancer Sci
Huang W, Xu F, Xu J, Quan G, Zhang S, Guo M, Xiao F, Jiang J.   +7 more
europepmc   +1 more source

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

MedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu, Zhi‐Shan Ge, Qing‐Yue Cao, Zi‐Han Li, An Zhang, Hai‐Dong Zhu, Gao‐Jun Teng   +6 more
wiley   +1 more source

Hedgehog Signaling Plays a Critical Role in Directing Correct Primordial Follicle Formation in the Mouse Ovary

, 2009
Heather Phillips
openalex   +1 more source

TGF-β1/SMAD3-mediated Non-canonical Hedgehog Signaling Promotes Pancreatic Stellate Cell Activation and Fibrosis in Chronic Pancreatitis. [PDF]

Int J Biol Sci
Peng L, Hu Y, Zhang X, Tan C, Yang C, Liu T, Ferdek PE, Yin S, Wang L, Huang W, Zhang Y.   +10 more
europepmc   +1 more source

Fraternal cooperation of hierarchical cancer parallels metazoan multicellularity and eusociality

Biological Reviews, Volume 101, Issue 1, Page 400-418, February 2026.
ABSTRACT Metazoan multicellularity and eusociality — both outcomes of the fraternal major transitions — have numerous features in common such as uneven distribution of group‐establishing potential. In addition to this framework, I argue herein that the group‐forming principles of metazoan multicellularity and eusociality are analogous to hierarchical ...
Jibeom Choi
wiley   +1 more source

Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng, Belén Lucas, Philipp Lampe, Stefano Ugel, Suyuan Chen, Anke Unger, Matthias Bischoff, Soheila Rezaei Adariani, Kesava Reddy Naredla, Kamal Kumar, Annika Schmidt, Carsten Strohmann, Petra Janning, Raphael Gasper, María Lucas, Malte Gersch, Sonja Sievers, Vincenzo Bronte, Slava Ziegler, Herbert Waldmann   +19 more
wiley   +2 more sources

Veratramine Inhibits Human Non-Small Cell Lung Cancer Cell Growth by Inhibiting the Hedgehog Signaling Pathway. [PDF]

J Pharmacopuncture
Lee SW, Kim HY, Kim W, Baek SM, Park JK, Park S, Han JE, Jo A, Seah E, Kim C, Lee J, Choi SK, Han S.   +12 more
europepmc   +1 more source