Results 271 to 280 of about 4,715,625 (390)

Hedgehog signaling inhibitors in solid and hematological cancers.

Cancer Treatment Reviews, 2019
J. Cortes, R. Gutzmer, M. Kieran, J. Solomon   +3 more
semanticscholar   +1 more source

Treatment‐Free Remission in Chronic Myeloid Leukemia: Revisiting the “W” Questions

European Journal of Haematology, EarlyView.
ABSTRACT Chronic myeloid leukemia (CML) has undergone a transformation from a fatal disease to a chronic, manageable condition with the advent of tyrosine kinase inhibitors (TKIs), particularly imatinib. This shift has significantly improved survival rates, and for some patients, achieving deep molecular response (DMR) has made treatment‐free remission
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Nicola Amodio, Caterina Labanca, Francesco Mendicino, Eugenio Lucia, Virginia Olivito, Fortunato Morabito, Massimo Gentile   +9 more
wiley   +1 more source

NME7 maintains primary cilium assembly, ciliary microtubule stability, and Hedgehog signaling. [PDF]

Life Sci Alliance
Ji M, Cui W, Feng Q, Qi J, Wang X, Zhu H, Zhang W, Fu W.   +7 more
europepmc   +1 more source

Temporal and Spatial Effects of Sonic Hedgehog Signaling in Chick Eye Morphogenesis

, 2001
Xiang-Mei Zhang, Xian-Jie Yang
openalex   +1 more source

In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review

Epilepsia, EarlyView.
Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik, Elena Vianca, Alison Anderson, Muhammad Shahid Javaid, Terence J. O'Brien, Ana Antonic‐Baker   +5 more
wiley   +1 more source

A novel function forHedgehogsignalling in retinal pigment epithelium differentiation [PDF]

, 2003
Muriel Perron, Sébastien Boy, Marcos A. Amato, Andrea S. Viczian, Katja Koebernick, Tomas Pieler, William A. Harris   +6 more
openalex   +1 more source

Developmental and epileptic encephalopathy in patients with epilepsy due to hypothalamic hamartomas

Epilepsia, EarlyView.
Abstract Objective What factors influence cognition and behavior in patients with epilepsy caused by hypothalamic hamartoma (HH)? Methods We conducted a retrospective study of 103 patients referred to the Epilepsy Center in Freiburg, Germany, over the past 24 years.
Kathrin Wagner, Theo Demerath, Sarah Metzger, Friederike Niedermoser, Birgitta Metternich, Lisa Putzar, Horst Urbach, Victoria San Antonio‐Arce, Kerstin Alexandra Klotz, Andreas Schulze‐Bonhage   +9 more
wiley   +1 more source

Notch and Hedgehog Signaling Unveiled: Crosstalk, Roles, and Breakthroughs in Cancer Stem Cell Research. [PDF]

Life (Basel)
Iluta S, Nistor M, Buruiana S, Dima D.
europepmc   +1 more source

A review of the equine suspensory ligament: Injury prone yet understudied

Equine Veterinary Journal, EarlyView.
Abstract The suspensory ligament (SL) is a key component of the elaborate and highly adapted suspensory apparatus in the horse. In addition to contributing to stabilisation of the metacarpophalangeal joint, the SL has a spring like function to reduce the energetic cost of locomotion.
Deborah J. Guest, Helen L. Birch, Chavaunne T. Thorpe   +2 more
wiley   +1 more source

Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor species

, 2002
Shau-Yu Yung, Şölen Gökhan, Jennifer Jurcsak, Aldrín E. Molero, Joseph J. Abrajano, Mark F. Mehler   +5 more
openalex   +1 more source